阻塞性睡眠呼吸暂停与慢性阻塞性肺病及哮喘相关性的研究进展  

Exploring the Relationship between Obstructive Sleep Apnea,Chronic Obstructive Pulmonary Disease and Asthma

作　　者：翁晓芹 张希龙 王文晶 Weng Xiaoqin;Zhang Xilong;Wang Wenjing(Department of Respiratory and Critical Care Medicine,the Second Affiliated Hospital of Nanjing Medical University,Nanjing 210000;Department of Respiratory and Critical Care Medicine,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210000)

机构地区：[1]南京医科大学第二附属医院呼吸与危重症医学科,南京210000 [2]南京医科大学第一附属医院呼吸与危重症医学科,南京210000

出　　处：《国际老年医学杂志》2024年第6期717-722,共6页International Journal of Geriatrics

基　　金：国家自然科学基金项目(82270103,81600066)。

摘　　要：阻塞性睡眠呼吸暂停与慢性气道炎症性疾病(包括慢性阻塞性肺病和哮喘)是呼吸科常见病,在老年人中发病率更高。当其两两或三者合并存在时影响更大,称之为重叠综合征,临床上较为常见。重叠综合征有独特的疾病特征、高危因素、病理生理机制、症状、诊断及相应的治疗策略,本文对上述内容进行综述,为临床诊疗提供支持。Obstructive sleep apnea and chronic airway inflammatory diseases,such as chronic obstructive pulmonary disease(COPD)and asthma,are prevalent respiratory conditions,particularly among the elderly.These diseases significantly impact the health and quality of life of the general population.The coexistence of two or more of these conditions,known as overlap syndrome,exacerbates their impact and is frequently encountered in clinical practice.This article provides a comprehensive review of the progress in understanding overlap syndromes,focusing on their distinctive disease features,risk factors,pathophysiological mechanisms,symptoms,diagnostic approaches,and corresponding treatment strategies.

关 键 词：阻塞性睡眠呼吸暂停 慢性阻塞性肺病 哮喘 重叠综合征 

分 类 号：R563.9[医药卫生—呼吸系统] R766[医药卫生—内科学] R562.25[医药卫生—临床医学]