OSAHS人群的早筛研究及其睡眠质量与认知功能的相关性分析  

Early screening study of OSAHS population and correlation analysis of sleep quality and cognitive function in OSAHS population

作　　者：杨志龙 王晶晶 李璇 赵荣书 姚文 Yang Zhilong;Wang Jingjing;Li Xuan;Zhao Rongshu;Yao Wen(Health Management Center,Lanzhou First People's Hospital,Lanzhou,Gansu 730050,China)

机构地区：[1]兰州市第一人民医院健康管理中心,甘肃兰州730050

出　　处：《现代临床医学》2024年第6期409-412,共4页Journal of Modern Clinical Medicine

基　　金：兰州市卫生科技发展计划项目(2019-006)。

摘　　要：目的:探讨光电容积脉搏波描计法(PPG)在阻塞性睡眠呼吸暂停低通气综合征(OSAHS)人群中的早筛价值,并进一步分析其睡眠质量与认知功能的相关性。方法:选取2019年12月至2020年2月在我院健康管理中心体检的211例体检者,同时进行整夜多导睡眠监测(PSG)及PPG监测,记录其睡眠指标数据,以PSG为金标准,分析评价PPG监测所得的数据;将纳入人群按PPG监测数据分为对照组(健康人群)和观察组(OSAHS人群),比较两组的总睡眠时间、觉醒次数、PSQI、MMSE和MoCA评分差异,并对睡眠指标与认知指标进行Pearson相关性分析。结果:PSG和PPG监测所得呼吸暂停低通气指数具有显著相关性(P<0.05);与PSG相比,PPG的灵敏度为86.1%,特异性为90.3%,R0C曲线下面积为0.931;观察组的觉醒次数、PSQI评分高于对照组,总睡眠时间、MMSE、MoCA评分低于对照组(P<0.05);OSAHS人群总睡眠时间与MMSE、MoCA评分呈正相关(r>0,P<0.05),觉醒次数、PQSI评分与MMSE、MoCA评分呈负相关(r<0,P<0.05)。结论:PPG可用于OSAHS的早期筛查,OSAHS人群的睡眠质量与认知功能存在相关性。Objective:To explore the early screening value of photoplethysmography(PPG)in obstructive sleep apnea hypopnea syndrome(OSAHS)population and further analyze the correlation between sleep quality and cognitive function in OSAHS population.Methods:A total of 21l examinees who underwent physical examination at the health management center of our hospital from December 2019 to February 2020 were selected.Overnight polysomnography(PSG)and PPG monitoring were performed simultaneously,and their sleep index data were recorded.Taking PSG as the gold standard,the data obtained by PPG monitoring were analyzed and evaluated.The included population was divided into control group(healthy people)and observation group(OSAHS population)according to PPG monitoring data.The differences in total sleep time,awakening times,PSQI,MMSE and MoCA scores between the two groups were compared.Pearson correlation analysis was performed on sleep indicators and cognitive indicators.Results:The apnea-hypopnea index obtained by PSG and PPG monitoring had a significant correlation(P<0.05).Compared with PSG,the sensitivity of PPG was 86.1%,the specificity was 90.3%,and the area under the ROC curve was O.931.The awakening times and PSQI scores of the observation group were higher than those of the control group,and the total sleep time,MMSE and MoCA scores were lower than those of the control group(P<0.05).In the OSAHS population,total sleep time was positively correlated with MMSE and MoCA scores(r>O,P<0.05),and awakening times and PQSI scores were negatively correlated with MMSE and MoCA scores(r<O,P<0.05).Conclusion:PPG can be used for early screening of OSAHS.There is a correlation between sleep quality and cognitive function in OSAHS population.

关 键 词：光电容积脉搏波描计法 阻塞性睡眠呼吸暂停低通气综合征 睡眠质量 认知功能 相关性分析 

分 类 号：R766[医药卫生—耳鼻咽喉科]