强直性脊柱炎合并冠心病患者的临床特征分析  

Analysis of clinical characteristics of patients with ankylosing spondylitis combined with coronary heart disease

作　　者：郭梦玲 郭雨凡[1] GUO Mengling;GUO Yufan(Department of Rheumatology and Immunology,Affiliated First Hospital,Soochow University,Suzhou 215026,CHINA)

机构地区：[1]苏州大学附属第一医院风湿免疫科,江苏215026

出　　处：《江苏医药》2024年第10期1040-1043,1047,共5页Jiangsu Medical Journal

摘　　要：目的分析强直性脊柱炎(AS)合并冠心病患者的临床特征。方法选取36例AS合并冠心病患者作为观察组,另选取同期住院治疗的36例单纯冠心病患者作为对照组,比较两组基本临床资料、实验室指标及超声心动图的差异。结果观察组冠心病发病年龄小于对照组(P<0.05)。观察组CRP、D-D、纤维蛋白原水平高于对照组(P<0.05)。观察组左心室舒张末期内径小于对照组(P<0.05)。结论与单纯冠心病患者相比,AS合并冠心病患者冠心病发病年龄更小,炎症反应程度更高,凝血-纤溶系统指标异常及心功能下降更明显。Objective To analyze the clinical characteristics of the patients with ankylosing spondylitis(AS)combined with coronary heart disease(CHD).Methods The differences in general data,laboratory indexes and echocardiograms were compared between the patients with AS combined with CHD(group A,36 cases)and the patients only with CHD(group B,36 cases).Results The age of CHD onset in group A was significantly younger than that in group B(P<0.05).The levels of C-reactive protein,D-dimer and fibrinogen in group A were significantly higher than those in group B(P<0.05).The end-diastolic internal diameter of the left ventricle in group A was significantly smaller than that in group B(P<0.05).Conclusion Compared with the patients with CHD alone,the patients with AS combined with CHD have younger age of CHD onset,higher degree of inflammatory response,and more pronounced abnormalities in coagulation-fibrinolytic system and decreased cardiac function.

关 键 词：强直性脊柱炎 冠心病 

分 类 号：R593[医药卫生—内科学]