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作 者:景泽 杨爽 黄燕 JING Ze;YANG Shuang;HUANG Yan(Clinical College of Traditional Chinese Medicine,Inner Mongolia Medical University,Hohhot 010000,China;Department of Pulmonary Disease,Inner Mongolia Hospital of Traditional Chinese Medicine,Hohhot 010000,China)
机构地区:[1]内蒙古医科大学中医临床医学院,内蒙古呼和浩特010000 [2]内蒙古自治区中医医院肺病科,内蒙古呼和浩特010000
出 处:《基层中医药》2024年第10期43-48,共6页Basic Traditional Chinese Medicine
基 金:内蒙古自治区科技计划项目(2021GG0268)。
摘 要:目的 探究慢性阻塞性肺疾病(COPD)稳定期患者应用中医综合慢病管理的临床效果。方法 按随机数字表法将2021年1—6月于内蒙古自治区中医医院诊断为COPD稳定期患者56例分为治疗组(28例)及对照组(28例),对照组根据COPD稳定期的分级制定治疗方案,在上述基础上治疗组实施中医综合慢病管理。比较两组急性加重入院次数、中医证候积分、慢性阻塞性肺病评估测试(CAT)评分、圣·乔治呼吸问卷(SGRQ)评分、6 min步行距离、肺功能指标及安全性。结果 治疗组干预后急性加重入院次数少于对照组(P <0.01),且干预后治疗组急性加重入院次数少于干预前(P <0.01)。治疗组干预后中医证候积分、CAT评分、SGRQ问卷评分均低于对照组(P <0.01),6 min步行距离长于对照组(P <0.05),用力肺活量(FVC)、第1秒用力呼气容积(FEV_(1))及FEV_(1)/FVC水平均高于对照组(P <0.05)。两组患者干预过程中肝肾功能及血常规均无明显异常。结论 COPD稳定期患者在中医综合慢病管理中能够有效减少急性加重发作次数,缓解各临床症状,提升肺功能,并可改善生活质量,安全可靠,值得推广应用。Objective To explore the clinical effect of traditional Chinese medicine(TCM)integrated chronic disease management in patients with stable chronic obstructive pulmonary disease(COPD).Methods A total of 56 patients diagnosed with stable COPD at the Inner Mongolia Hospital of Traditional Chinese Medicine from January to June 2021 were divided into a treatment group(28 cases) and a control group(28 cases) according to the random number table method.The control group received a treatment plan based on the grading of stable COPD,while the treatment group received TCM integrated chronic disease management in addition to this plan.The number of hospital admissions for acute exacerbations,TCM syndrome scores,Chronic Obstructive Pulmonary Disease Assessment Test(CAT) scores,St.George's Respiratory Questionnaire(SGRQ) scores,6-min walking distance,pulmonary function indexes,and safety were compared between the two groups.Results The number of acute exacerbation hospitalizations in the treatment group after intervention was significantly lower than that in the control group(P < 0.01),and it also decreased compared with that before intervention(P < 0.01).After the intervention,TCM syndrome scores,CAT scores,and SGRQ scores in the treatment group were lower than those in the control group(P < 0.01).The 6-min walking distance was longer in the treatment group than that in the control group(P < 0.05),and forced vital capacity(FVC),forced expiratory volume in one second(FEV1),and the FEV1/FVC ratio were higher in the treatment group(P < 0.05).No significant abnormalities in liver and kidney function or blood routine were observed in either group during the intervention.Conclusion TCM integrated chronic disease management can effectively reduce the frequency of acute exacerbations,relieve clinical symptoms,enhance lung function,and improve the quality of life in patients with stable COPD.This approach is safe and reliable,making it worthy of promotion and application.
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