超声内镜弹性成像技术联合谐波造影增强超声内镜在胰腺占位性病变中的诊断价值  

Diagnostic value of endoscopic ultrasound elastography combined with contrast enhanced harmonic endoscopic ultrasonography in pancreatic space occupying lesions

作　　者：孟现军 庞立厚 于冬 王竞 金城 MENG Xian-jun;PANG Li-hou;YU Dong(Department of Ultrasound,Fengfeng General Hospital,North China Medical and Health Group,Handan Hebei 056200,China;Department of Abdominal Ultrasound,The Second Hospital of Hebei Medical University,Shijiazhuang Hebei 050000,China)

机构地区：[1]华北医疗健康集团峰峰总医院超声科,河北邯郸056200 [2]河北医科大学第二医院腹部超声科,河北石家庄050000 [3]华北医疗健康集团峰峰总医院泌尿外科,河北邯郸056200

出　　处：《临床和实验医学杂志》2024年第19期2127-2128,F0003,共3页Journal of Clinical and Experimental Medicine

基　　金：河北省卫健委科研课题项目(编号:172777217)。

摘　　要：目的研究胰腺占位性病变检查中超声内镜弹性成像技术(EUS-EG)与谐波造影增强超声内镜(CEH-EUS)联合诊断的价值。方法以回顾性分析为法,观察对象为2022年1月至2023年6月华北医疗健康集团峰峰总医院收治的80例胰腺占位性病变患者,参考不同检查方式分为单一组(仅接受EUS-EG检查,n=80)与联合组(EUS-EG联合CEH-EUS检查,n=80)。比较两组患者的疾病检出率、误诊率、准确度、特异度及敏感度,并比较胰腺良性、恶性病变超声造影时相,观察CEH-EUS、EUS-EG影像学特点。结果以病理学检查结果为诊断金标准,80例胰腺占位性病变患者均行手术切除处理,病理学检验显示44例为良性病变,36例为恶性病变。两组患者疾病检出率差异无统计学意义(P>0.05);联合组疾病误诊率(5.00%)明显低于单一组(30.00%),差异有统计学意义(P<0.05)。联合组诊断准确性、敏感度分别为95.00%、97.36%,均明显高于单一组(70.00%、67.85%),差异均有统计学意义(P<0.05);两组诊断特异度比较,差异无统计学意义(P>0.05)。良性病变的超声造影时相早增晚退、同增同退率分别为22.72%、54.54%,均明显高于恶性病变(0、0),晚增早退率为13.63%,低于恶性病变(55.56%),差异均有统计学意义(P<0.05)。结论EUS-EG与CEH-EUS联合诊断胰腺占位性病变的准确性和敏感度均高于单纯EUS-EG检测,可有效减少误诊。Objective To study the diagnostic value of endoscopic ultrasound elastography(EUS-EG)combined with contrast enhanced harmonic endoscopic ultrasonography(CEH-EUS)in pancreatic space occupying lesions.Methods By retrospective analysis,80 patients with pancreatic space occupying lesions admitted to Fengfeng General Hospital,North China Medical and Health Group from January 2022 to June 2023 were divided into the single group(EUS-EG only,n=80)and the combined group(EUS-EG combined with CEH-EUS,n=80)according to different examination methods.The detection rate,misdiagnosis rate,accuracy,specificity and sensitivity of the two groups were compared,and the contrast-enhanced ultrasound phases of benign and malignant pancreatic lesions were compared to observe the imaging characteristics of CEH-EUS and EUS-EG.Results Based on the results of pathological examination,80 patients with pancreatic space-occupying lesions underwent surgical resection.Pathological examination showed 44 cases of benign lesions and 36 cases of malignant lesions.There was no statistically significant difference in disease detection rate between the two groups(P>0.05).The misdiagnosis rate of the combined group(5.00%)was significantly lower than that of the single group(30.00%),and the difference was statistically significant(P<0.05).The diagnostic accuracy and sensitivity of combined group were 95.00%,97.36%,which were significantly higher than those of single group(70.00%,67.85%),and the differences were statistically significant(P<0.05).There was no statistically significant difference in diagnostic specificity between the two groups(P>0.05).The ratios of contrast-enhanced ultrasound phase early increase and late retreat,simultaneous increase and retreat of benign lesions were 22.72%and 54.54%,respectively,which were significantly higher than those of malignant lesions(0,0),the rate of late increase and early retreat was 13.63%,which was lower than that of malignant lesions(55.56%),and the differences were statistically significant(P<0.05).Conclus

关 键 词：胰腺 诊断 超声内镜弹性成像 谐波造影增强超声内镜 

分 类 号：R445.1[医药卫生—影像医学与核医学] R735.9[医药卫生—诊断学]