利伐沙班片在心房颤动患者射频消融术后抗凝治疗中的效果分析  

Effect of Rivaroxaban Tablets on Anticoagulation Therapy in Patients with Atrial Fibrillation after Radiofrequency Ablation

作　　者：张艳霞 刘圣桂 ZHANG Yanxia;LIU Shenggui(Department of Pharmacy Dispensing Management,Ffixian People’s Hospital,Linyi 273400,China;Department ofVasculocardiology,Ffixian People’s Hospital,Linyi 273400,China)

机构地区：[1]山东省费县人民医院门诊药品调配管理科,山东临沂273400 [2]山东省费县人民医院心血管内科,山东临沂273400

出　　处：《中国伤残医学》2024年第14期88-91,共4页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的:探讨利伐沙班片在心房颤动(AF)患者射频消融术后抗凝治疗中的效果。方法:选取2023年7月—2024年1月费县人民医院收治的55例AF患者为研究对象,按随机数字表法将其随机分为研究组(n=30)与对照组(n=25)。所有患者均接受射频消融术治疗,术后对照组采用华法林钠片进行治疗,研究组采用利伐沙班片进行治疗。比较两组治疗效果、出血情况、凝血功能及手术相关指标。结果:治疗后,研究组血栓栓塞事件发生率为3.33%,低于对照组的20.00%,差异有统计学意义(P<0.05);两组治疗有效率、出血情况、凝血功能、手术相关指标比较,差异均无统计学意义(P>0.05)。结论:利伐沙班片显著降低了AF患者射频消融术治疗后血栓栓塞的发生风险,且对患者的出血情况、凝血功能及手术相关指标无显著影响,具备一定的有效性及安全性。Objective:To investigate the anticoagulant effect of Rivaroxaban Tablets in the treatment of atrial fibrillation(AF)patients after radiofrequency ablation.Methods:A total of 55 patients with AF admitted to Fei County People’s Hospital from July 2023 to Janury 2024 were selected as the study objects.They were randomly divided into a study group(n=30)and a control group(n=25)according to random number table method.All patients received radiofrequency ablation.After surgery,the control group was treated with Warfarin Sodium Tablets and the study group was treated with Rivaroxaban Tablets.The therapeutic effect,bleeding situation,coagulation function and operation related indexes were compared between the two groups.Results:After treatment,the incidence of thromboembolic events in the study group was 3.33%,which was lower than20.00%in the control group,with statistical significance(P<0.05).There were no significant differences in treatment efficiency,bleeding situation,coagulation function and surgical related indexes between the two groups(P>0.05).Conclusion:Rivaroxaban Tablet can significantly reduce the risk of thromboembolism in AF patients after radiofrequency ablation,and has no significant effect on bleeding,coagulation function and surgery-related indicators,and it has certain effectiveness and safety.

关 键 词：心房颤动 利伐沙班片 抗凝 疗效 

分 类 号：R541[医药卫生—心血管疾病]