儿童克罗恩病不同疾病活动度评估方法研究进展  

Research progress of different evaluation methods of disease activity in children with Crohn's disease

作　　者：邓文 李中跃[1,2] DENG Wen;LI Zhong-yue(Department of Gastroenterology,Children's Hospital of Chongqing Medical University,National Clinical Research Center for Child Health and Disorders,Ministry of Education Key Laboratory of Child Development and Disorders,China Intemational Science and Technology Cooperation Base of Child Development and Critical Disorders,Chonging Key Laboratory of Pediatrics,Chongqing 400014,China)

机构地区：[1]重庆医科大学附属儿童医院消化科,国家儿童健康与疾病临床医学研究中心,儿童发育疾病研究教育部重点实验室,儿童发育重大疾病国家国际科技合作基地,儿科学重庆市重点实验室,重庆400014 [2]浙江大学医学院附属第四医院儿科,浙江义乌322000

出　　处：《中国实用儿科杂志》2024年第10期785-791,共7页Chinese Journal of Practical Pediatrics

摘　　要：克罗恩病(Crohn's disease,CD)是一种可累及全肠道的慢性肉芽肿性炎性疾病。儿童CD临床表现多样,特点为活动期与缓解期交替,有终身复发倾向,随病程发展严重影响患儿生存质量。综合评估患者临床表现、影像学表现、内镜检查及实验室指标可判断疾病活动度、严重程度,对指导疾病的治疗具极大的意义。文章阐述CD不同类型的疾病活动度评估方法研究进展,以期为临床合理干预及疾病长期监测提供参考依据。Crohn's disease is a chronic granulomatous inflammatory disease involving the whole intestine.Children's clinical manifestations of CD are diverse,characterized by alternating active period and remission period,which have the tendency of lifelong recurrence.With the development,the quality of life of patients can be affectedseriously.Pediatricians have to evaluate the disease activity through the clinical feature,imaging findings,endoscopy and laboratory indicators,which is of great significance for the treatments.The Objectiveof this paper is to review and summarize the progress of different types of evaluation methods,in order to provide reference for rational clinical intervention and long-term monitoring of diseases.

关 键 词：儿童 克罗恩病 疾病活动度 内镜评分 

分 类 号：R72[医药卫生—儿科]