2017—2023年连云港市海州区围生儿出生缺陷监测结果分析  

Analysis of monitoring results of perinatal birth defects in Haizhou District, Lianyungang City from 2017 to 2023

作　　者：徐娟 刘月芳 宋云云 吴启秀 吴春林 潘琼[1,3] XU Juan;LIU Yuefang;SONG Yunyun;WU Qixiu;WU Chunlin;PAN Qiong(Medical College of Yangzhou University,Yangzhou,Jiangsu 225000,China;Women’s Health Care Department,Haizhou District Maternal and Child Health Care Institute,Lianyungang,Jiangsu 222000,China;Genetic and Prenatal Diagnosis Department,Huai’an Maternal and Child Health Hospital,Huai’an,Jiangsu 223002,China)

机构地区：[1]扬州大学医学院,江苏扬州225000 [2]海州区妇幼保健所妇女保健科,江苏连云港222000 [3]淮安市妇幼保健院遗传与产前诊断科,江苏淮安223002

出　　处：《中国优生与遗传杂志》2024年第9期1918-1922,共5页Chinese Journal of Birth Health & Heredity

摘　　要：目的分析连云港市海州区2017—2023年围生儿出生缺陷发生情况及分布特征,为完善本地区出生缺陷预防策略和干预效果评价提供参考依据。方法收集2017年1月至2023年10月连云港市海州区所有助产机构分娩的全部缺陷儿监测记录数据进行统计分析。结果近7年间,连云港市海州区共分娩围生儿95317例,出生缺陷儿1171例,围生儿出生缺陷发生率为122.85/万;在不同特征别中,城镇人口的发生率为130.77/万,显著高于农村的(112.75/万);男婴发生率为131.42/万,显著高于女婴的(112.91/万);<20岁年龄组出生缺陷发生率最高(167.77/万),其次为≥35岁年龄组(164.39/万)。先天性心脏病在所有年份中均为第一顺位出生缺陷,发生率呈波动性上升趋势,在2019年达到最高(82.63/万)。结论2017—2023年连云港市海州区围生儿出生缺陷的发生率低于全国水平,发生率呈波动上升趋势,以先天性心脏病发生率升高为主,建议重点加强对常见出生缺陷尤其是先天性心脏病的产前筛查和诊断水平。同时低龄产妇及高龄产妇的出生缺陷发生率较高,应针对这两个年龄组加强健康宣教和孕期优生检查。Objective To provide references for improving strategies in preventing birth defects and assessing the effectiveness of interventions in the local community of Haizhou District,Lianyungang City.Methods The study utilized a testing method centered on maternity hospitals,collecting and analyzing data on the occurrence and distribution patterns of birth defects in perinatal infants in Haizhou District,Lianyungang City from January 2017 to October 2023.Results Over the last seven years,a total of 95317 perinatal infants were born in Haizhou District,with 1171 infants exhibiting birth defects.The incidence rate of birth defects was 122.85 per 10000 births.Notably,the incidence rate among the urban population was 130.77 per 10000 births,which was notably higher than 112.75 per 10000 births in the rural population.Similarly,the incidence rate for male infants at 131.42 per 10000 births was significantly higher than that for females,which was 112.91 per 10000 births.The age group<20 years recorded the highest incidence rate(167.77 per 10000 births),followed by those≥35 years(164.39 per 10000 births).Congenital heart disease consistently maintained its position as the most common birth defect throughout the seven years examined in this study,displaying a fluctuating upward trend,reaching its peak in 2019(82.63 per 10000 births).Conclusion From 2017 to 2023,the incidence rate of birth defects in perinatal infants born in Haizhou District,Lianyungang City remained below the national average.However,a fluctuating upward trend was observed,primarily driven by an increase in the incidence of congenital heart disease.Therefore,the study recommends a concentrated effort on enhancing prenatal screening and diagnostic capabilities,particularly for common birth defects such as congenital heart disease.At the same time,younger mothers(aged<20)and older mothers(aged≥35)were observed to have relatively higher incidence of birth defects,and health education of birth defects should be reinforced for these age groups.

关 键 词：围生儿 出生缺陷 监测分析 发生率 

分 类 号：R174[医药卫生—妇幼卫生保健]