SPECT/CT融合显像在肺灌注平面显像单侧肺不显影病因诊断中的增益价值  

Analysis of the added value of SPECT/CT fusion imaging in the etiological diagnosis of unilateral absence in planar pulmonary perfusion imaging

作　　者：王茸 王永乐 刘自强 苏新 陈得魁 杨莉桢 王海军[1] 谢萍[4] Wang Rong;Wang Yongle;Liu Ziqiang;Su Xin;Chen Dekui;Yang Lizhen;Wang Haijun;Xie Ping(Department of Nuclear Medicine,Gansu Provincial Hospital,Lanzhou 730000,China;Department of Radiology,Qin'an County Ye Bao Township Hospital,Tianshui 741607,China;Department of Orthopedics,the 2nd Affiliated Hospital of Chengdu Medical College,Nuclear Industry 416 Hospital,Chengdu 610051,China;Department of Cardiology,Gansu Provincial Hospital,Lanzhou 730000,China)

机构地区：[1]甘肃省人民医院核医学科,兰州730000 [2]秦安县叶堡中心卫生院放射科,天水741607 [3]成都医学院第二附属医院·核工业四一六医院骨科,成都610051 [4]甘肃省人民医院心内科,兰州730000

出　　处：《国际放射医学核医学杂志》2024年第8期477-483,共7页International Journal of Radiation Medicine and Nuclear Medicine

基　　金：甘肃省自然科学基金(23JRRA1315);甘肃省人民医院院内科研项目(22GSSYD-13)。

摘　　要：目的探讨SPECT/CT融合显像在肺灌注平面显像单侧肺不显影患者的病因诊断中的增益价值。方法回顾性分析2019年1月至2022年7月于甘肃省人民医院行肺灌注平面显像,结果表现为单侧肺不显影的29例患者的临床资料,其中男性14例、女性15例,年龄(59.8±11.1)岁。所有患者均行SPECT/CT融合显像,并经肺动脉CT血管成像、肺动脉造影及临床资料最终明确诊断。根据病因,将患者分为肺血管病变组和肺部病变组,通过SPECT/CT融合显像分析2组患者单侧肺不显影的病因,记录并比较2组患者的实验室检查结果,组间比较采用独立样本t检验或Mann-Whitney U检验。结果肺血管病变组12例,其中肺血管炎7例(58.3%)、纤维素性纵隔炎4例(33.3%)、先天性右肺动脉缺如1例(8.3%)。肺部病变组17例,其中胸腔积液8例(47.1%)、肺门肿瘤3例(17.6%)、肺气肿1例(5.9%)、肺大泡1例(5.9%)、左侧肺不张1例(5.9%)、左侧胸廓塌陷1例(5.9%)、左肺术后缺如1例(5.9%)、机化性肺炎1例(5.9%)。2组患者的实验室检查结果中除血氧分压的差异有统计学意义外(t=-2.681,P<0.05),其余实验室检查结果的差异均无统计学意义(Z=-1.900~-0.296,t=-1.313~0.917,均P>0.05)。结论与肺灌注平面显像相比,SPECT/CT融合显像可以提供更多有价值的信息,对单侧肺不显影患者的病因诊断具有增益价值。ObjectiveTo explore the added value of SPECT/CT fusion imaging in the etiological diagnosis of patients with unilateral absence in planar pulmonary perfusion imaging.MethodsA retrospective analysis was performed on 29 patients(14 males and 15 females,aged 59.8±11.1 years)with unilateral absence who received pulmonary perfusion plane imaging from January 2019 to July 2022 in Gansu Provincial Hospital.All patients underwent SPECT/CT fusion imaging,and the final diagnosis was confirmed through pulmonary artery CT angiography,pulmonary angiography,and clinical data.In accordance with the etiology,the patients were divided into pulmonary vascular disease group and pulmonary disease group.The etiology of unilateral lung opacities in the two groups was analyzed through SPECT/CT fusion imaging.The laboratory test results of the two groups of patients were recorded and compared.Independent sample t-test or Mann-Whitney U test was used for intergroup comparison.ResultsThe pulmonary vascular disease group consisted of 12 cases,including 7 cases(58.3%)of pulmonary vasculitis,4 cases(33.3%)of fibrosing mediastinitis,and 1 case(8.3%)of congenital absence of right pulmonary artery.The pulmonary disease group had 17 cases,including 8 cases(47.1%)of pleural effusion,3 cases(17.6%)of hilar tumor,1 case(5.9%)of emphysema,1 case(5.9%)of pulmonary bullae,1 case(5.9%)of left atelectasis,1 case(5.9%)of left thoracic collapse,1 case(5.9%)of postoperative absence of left lung,and 1 case(5.9%)of organized pneumonia.No significant differences were found in the results of laboratory tests between the two groups(Z=-1.900 to-0.296,t=-1.313 to 0.917,all P>0.05)except blood oxygen partial pressure(t=-2.681,P<0.05).ConclusionSPECT/CT fusion imaging can provide more valuable information than planar imaging.It has added value in the etiological diagnosis of patients with unilateral absence in planar pulmonary perfusion imaging.

关 键 词：肺灌注显像 肺栓塞 体层摄影术 发射型计算机 单光子 体层摄影术 X线计算机 

分 类 号：R816.4[医药卫生—放射医学] R563.5[医药卫生—临床医学]