特应性皮炎发病机制研究进展  

Research Progress in Pathogenesis of Atopic Dermatitis

作　　者：张慧娟 朱雅琳[1] ZHANG Huijuan;ZHU Yalin(Department of Dermatology and Venereology,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830000,China)

机构地区：[1]新疆医科大学第一附属医院皮肤与性病学科,乌鲁木齐830000

出　　处：《医学综述》2024年第23期2839-2843,共5页Medical Recapitulate

摘　　要：特应性皮炎(AD)的发病机制可能与遗传、免疫、菌群失调、皮肤屏障功能等因素相关,目前病因尚不明确。随着AD发病率的不断增加,人们对AD发病机制的研究逐渐深入,以进一步深入了解直接或间接影响AD发病的因素。虽然近年对AD的理解有了显著提高,但仍迫切需要寻找有效、安全和有针对性的治疗中度至重度AD的方法。未来,AD发病机制将逐渐明确,且可能找到新的AD治疗思路和更为有效的治疗方法。The pathogenesis of atopic dermatitis(AD)may be related to genetic,immune,dysbiosis,and skin barrier function factors,and the etiology is currently unclear.With the increasing incidence of AD,the research on the pathogenesis of AD has gradually deepened,so as to further understand the factors that directly or indirectly affect the pathogenesis of AD.Although there has been a significant improvement in understanding AD in recent years,there is still an urgent need to find effective,safe,and targeted methods for treating moderate to severe AD.In the future,the pathogenesis of AD will gra-dually be clarified,and new treatment ideas and more effective treatment methods for AD may be discovered.

关 键 词：特应性皮炎 分子机制 免疫功能障碍 菌群失调 表观遗传机制 皮肤屏障功能 

分 类 号：R758.2[医药卫生—皮肤病学与性病学]