女性原发性冻结肩发病与血清性激素水平的相关性研究  

Correlation analysis between female primary frozen shoulder disease and serum sex hormone level

作　　者：潘耀峰 吕云 张素娟 范雪梅 Pan Yaofeng;Lv Yun;Zhang Sujuan;Fan Xuemei(Sinopharm Tongmei General Hospital,Datong,Shanxi 037003,China)

机构地区：[1]国药同煤总医院,山西大同037003

出　　处：《首都食品与医药》2024年第21期31-34,共4页Capital Food Medicine

摘　　要：目的探讨血清性激素水平与女性原发性冻结肩患者发病的相关性。方法选取2017年12月-2022年9月,国药同煤总医院康复科门诊、住院收治的女性原发性冻结肩患者57例,分为绝经期组33例、绝经过渡期组24例,同期健康体检者53例为对照组(绝经期对照组33例、绝经过渡期对照组20例)。收集测试者的临床资料,均进行血清性激素水平检测,包括促卵泡生成素(FSH)、促黄体生成素(LH)、雌二醇(E2)、孕酮(P)、泌乳素(PRL)、睾酮(T),对数据进行统计学分析。结果原发性冻结肩绝经期组患者雌二醇(E2)浓度明显低于正常绝经期对照组(P<0.01);促卵泡生成素(FSH)、促黄体生成素(LH)的浓度明显高于对照组(P<0.01);原发性冻结肩绝经期组孕酮(P)、泌乳素(PRL)、睾酮(T)与正常绝经期对照组差异无统计学意义(P>0.05)。原发性冻结肩绝经过渡期组患者血清E2浓度明显低于正常绝经过渡期对照组(P<0.01);原发性冻结肩绝经过渡期组患者血清FSH、LH、PRL的浓度明显高于绝经过渡期对照组(P<0.05);原发性冻结肩绝经过渡期组患者T、P与正常绝经过渡期对照组差异无统计学意义(P≥0.05)。结论女性原发性冻结肩的发病与血清性激素水平具有相关性。女性体内雌激素水平下降可导致原发性冻结肩发生,可为其在临床中诊治提供一定的参考依据。Objective To explore the correlation between sex hormone levels and the onset of female patients with primary frozen shoulder.Methods From December 2017 to September 2022,57 cases of female patients with primary frozen shoulder were selected,which were divided into menopausal group(33 cases)and menopausal transition group(24 cases),and 53 healthy people in our hospital as control group(33 cases in menopausal group and 20 cases in menopausal transition group).Collect clinical data of testers and conduct serum hormone level testing,including follicle stimulating hormone(FSH),luteinizing hormone(LH),estradiol(E2),progesterone(P),prolactin(PRL),testosterone(T),and perform statistical analysis on the data.Results The concentration of estradiol(E2)in the primary frozen shoulder menopause group was significantly lower than that in the normal menopause control group(P<0.01).The concentrations of follicle stimulating hormone(FSH)and luteinizing hormone(LH)were significantly higher than those in the control group(P<0.01).There was no significant difference in progesterone(P),prolactin(PRL)and testosterone(T)between primary frozen shoulder menopause group and normal menopause control group(P>0.05).The concentration of serum E2 in patients with primary frozen shoulder menopause transition group was significantly lower than that in normal menopause transition group(P<0.01).The concentrations of serum FSH,LH and PRL in the primary frozen shoulder menopause transition group were significantly higher than those in the menopausal transition group(P<0.05).There was no significant difference in T and P between the primary frozen shoulder menopause transition group and the normal control group(P≥0.05).Conclusion The incidence of female primary frozen shoulder is related to the level of sex hormones.The decrease of estrogen level in women can lead to the occurrence of primary frozen shoulder,which can provide some reference for its clinical diagnosis and treatment.

关 键 词：冻结肩 肩周炎 性激素 相关性 病因 

分 类 号：R684.3[医药卫生—骨科学]