阴茎头局部注射透明质酸治疗早泄的方法详解和经验分享  

Detailed explanation and experience sharing of local injection of hyaluronic acid into glans penis for the treatment of premature ejaculation

作　　者：张晓威[1,2] 何海龙[3] 胡显辉 ZHANG Xiaowei;HE Hailong;HU Xianhui(Department of Urology,Peking University People's Hospital,Beijing 100044;Institute of Applied Lithotripsy Technology,Peking University,Beijing 100044;Department of Urology,The Third Affiliated Hospital of Chongqing Medical University,Chongqing 401120;Department of Urology,Chengdu First People's Hospital,Chengdu 610016,China)

机构地区：[1]北京大学人民医院泌尿外科,北京100044 [2]北京大学应用碎石技术研究所,北京100044 [3]重庆医科大学附属第三医院泌尿外科,重庆401120 [4]成都市第一人民医院泌尿外科,四川成都610016

出　　处：《现代泌尿外科杂志》2024年第11期945-950,共6页Journal of Modern Urology

摘　　要：早泄(PE)是男性常见的射精功能障碍,发病率较高,是导致患者及其伴侣性满意度低的常见原因。其病因复杂,受到心理、解剖、神经生物和行为医学等因素影响,难以彻底治愈。目前针对PE的治疗,除了心理干预、局部麻醉剂、达泊西汀等药物和手术治疗外,透明质酸(HA)凝胶注射也是一种可替代的治疗方法。该方法通过阴茎头局部皮下注射HA凝胶来阻断神经末梢的感觉传入,降低阴茎头的敏感性,延长患者阴道内射精潜伏时间,提高患者及其伴侣性满意度。HA凝胶具有安全性及耐受性高等优点,是一种有前景的临床应用材料。本文在探讨PE的其他疗法的同时,详细介绍了HA凝胶注射治疗的注射技术、有效性和安全性。Premature ejaculation(PE),a common ejaculatory dysfunction in men with high prevalence,is a frequent cause of low sexual satisfaction for both patients and their partners.The etiology of PE is complex,including psychological,anatomical,neurobiological,and behavioral medicine factors,making it difficult to cure.Currently,treatments of PE include psychological interventions,local anesthetics,medications such as dapoxetine,and surgical treatments.Hyaluronic acid(HA)gel injection is an alternative treatment method.By subcutaneously injecting HA gel into the glans penis,the sensory input from nerve endings can be blocked,thereby reducing glans sensitivity.This approach can significantly extend the intravaginal ejaculatory latency time(IELT)and improve patient satisfaction.Moreover,it has advantages such as safety and high tolerability,making it a promising treatment option.In this paper,the technique,efficacy and safety of HA injection therapy for PE are introduced in detail on the basis of exploring other therapies for PE.

关 键 词：早泄 透明质酸 局部注射 阴道内射精潜伏时间 

分 类 号：R698[医药卫生—泌尿科学]