冠状动脉周围脂肪组织在冠心病中的临床意义  

The clinical significance of pericoronary adipose tissue in coronary heart disease

作　　者：杨彩凤 邓婵翠 石蓓 许官学 YANG Caifeng;DENG Chancui;SHI Bei;XU Guanxue(The First Clinical College of Zunyi Medical University;Department of Cardiovascular Medicine,Affiliated Hospital of Zunyi Medical University,Zunyi,Guizhou 563000,China)

机构地区：[1]遵义医科大学第一临床学院 [2]遵义医科大学附属医院心血管内科,贵州省遵义市563000

出　　处：《中国动脉硬化杂志》2024年第11期999-1005,共7页Chinese Journal of Arteriosclerosis

基　　金：贵州省科技计划项目(黔科合成果-LC[2021]026)。

摘　　要：冠状动脉周围脂肪组织(PCAT)在心血管疾病中的调节作用至关重要。PCAT通过分泌多种生物活性物质,如脂肪因子和细胞因子,对心血管系统产生广泛的病理生理作用。目前,通过冠状动脉计算机体层成像血管造影可以检测PCAT的衰减值,这不仅能够反映血管炎症水平,还在冠心病斑块检测及预后评估中具有重要的临床价值。因此,该文综述了PCAT的病理生理机制及其在冠心病中的临床意义。The regulatory role of pericoronary adipose tissue(PCAT)in cardiovascular diseases is of paramount im-portance.PCAT exerts extensive pathophysiological effects on the cardiovascular system by secreting various bioactive substances,such as adipokines and cytokines.Currently,the attenuation value of PCAT can be detected via coronary computed tomography angiography(CCTA),a method that not only reflects the level of vascular inflammation but also holds significant clinical value in the detection and prognostic assessment of coronary heart disease plaques.Therefore,this article reviews the pathophysiological mechanisms of PCAT and its clinical significance in coronary heart disease.

关 键 词：冠状动脉周围脂肪组织 血管炎症 冠心病 

分 类 号：R445[医药卫生—影像医学与核医学] R5[医药卫生—诊断学]