小剂量丙泊酚结合右美托咪定、舒芬太尼在宫腔镜手术麻醉中的作用  

Role of Low-dose Propofol Combined with Dexmedetomidine and Sufentanil in Hysteroscopic Surgery Anesthesia

作　　者：董博雅 Dong Boya(Department of Anesthesiology,Jingdong Zhongmei Hospital,Langfang 065201,Hebei Province,China)

机构地区：[1]京东中美医院麻醉科,河北廊坊065201

出　　处：《中外医药研究》2024年第28期66-69,共4页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:探讨小剂量丙泊酚结合右美托咪定、舒芬太尼在宫腔镜手术麻醉中的效果。方法:选取2020年12月—2023年2月京东中美医院收治的宫腔镜手术患者70例为研究对象,按随机分组法分为对照组与观察组,各35例。对照组应用小剂量丙泊酚和舒芬太尼麻醉,观察组应用小剂量丙泊酚、舒芬太尼和右美托咪定麻醉。对比两组血流动力学指标、麻醉深度与镇痛情况、麻醉相关指标、镇静合格率。结果:麻醉后即刻、扩宫时、输卵管插管时、手术结束时,观察组呼吸频率、平均动脉压、经皮血氧饱和度、心率水平高于对照组(P<0.05);麻醉后即刻、扩宫时、输卵管插管时、手术结束时,观察组镇静深度优于对照组,镇痛深度优于对照组(P<0.001);观察组麻醉起效时间、睁眼时间、呼吸恢复时间、清醒时间、定向力恢复时间、拔管时间均短于对照组,苏醒后数字评分量表评分低于对照组(P<0.001);观察组镇静合格率高于对照组(P=0.001)。结论:小剂量丙泊酚、右美托咪定、舒芬太尼干预效果较好,能够有效维持患者麻醉期间的血流动力学稳定,镇静和镇痛深度较好,患者麻醉恢复速度较快,疼痛程度较轻。Objective:To investigate the effect of low-dose propofol combined with dexmedetomidine and sufentanil in anesthesia for hysteroscopic surgery.Methods:Seventy cases of hysteroscopic surgery patients admitted to Jingdong Zhongmei Hospital from December 2020 to February 2023 were selected for the study,and were divided into the control group and the observation group according to the randomized grouping method,thirty-five cases each.The control group was anesthetized with low-dose propofol and sufentanil,and the observation group was anesthetized with low-dose propofol,sufentanil and dexmedetomidine.The hemodynamic indexes,depth of anesthesia and analgesia,anesthesia-related indexes,and sedation pass rate were compared between the two groups.Results:Immediately after anesthesia,at the time of uterine dilatation,at the time of tubal cannulation,and at the end of surgery,the respiratory rate,mean arterial pressure,transcutaneous oxygen saturation,and heart rate levels of the observation group were higher than those of the control group(P<0.05);immediately after anesthesia,at the time of uterine dilatation,at the time of tubal cannulation,and at the end of surgery,the depth of sedation in the observation group was better than that of the control group,and the depth of analgesia was better than that of the control group(P<0.001);the onset time of anesthesia,eye opening time,respiratory recovery time,awake time,orientation recovery time,and extubation time of the observation group were shorter than that of the control group,and the score of the Numerical Rating Scale after awakening was lower than that of the control group(P<0.001);the sedation pass rate of the observation group was higher than that of the control group(P=0.001).Conclusion:Low-dose propofol,dexmedetomidine,and sufentanil interventions were more effective in maintaining hemodynamic stability during anesthesia,with better depth of sedation and analgesia,faster recovery from anesthesia,and less pain in patients.

关 键 词：小剂量丙泊酚 右美托咪定 舒芬太尼 宫腔镜手术 

分 类 号：R614[医药卫生—麻醉学]