初始进入腹膜透析的糖尿病肾病冠状动脉钙化危险因素分析  

Analysis of Coronary Artery Calcification Risk Factors in Diabetic Kidney Disease Patients Initiating Peritoneal Dialysis

作　　者：赵盼 ZHAO Pan(Kaifeng Central Hospital,Kaifeng 475000,Henan Province,China)

机构地区：[1]开封市中心医院,河南开封475000

出　　处：《罕少疾病杂志》2024年第11期63-64,共2页Journal of Rare and Uncommon Diseases

摘　　要：目的探讨行腹膜透析(PD)的糖尿病肾病(DKD)患者冠状动脉钙化(CAC)情况及危险因素的分析。方法选取2020年1月至2022年12月于开封市中心医院就诊并进入PD治疗的62例DKD患者,治疗6个月后行胸部CT检查,计算冠状动脉钙化指数(CACs),并收集患者的一般资料、临床检验结果进行统计学分析,了解CAC的发生率及危险因素。结果初始进入PD治疗的DKD患者62例,其中CAC患者22例(35.48%)。钙化组相较于无钙化组,患者的年龄更大,P、PTH、OPG水平更高,差异具有统计学意义(P<0.05)。在性别、吸烟、BMI、SBP、DBP、CR、BUN、UA、HB、ALB、TC、TG、Ca水平,两组间均无无显著差异(P>0.05)。经二元Logistic回归分析显示血P、OPG是CAC的独立危险因素。结论血P、OPG水平越高,初始进入PD治疗的DKD患者发生CAC的风险更大。Objective To investigate the coronary artery calcification(CAC)and risk factors in patients with diabetic kidney disease(DKD)undergoing peritoneal dialysis(PD).Methods 62 patients with DKD who underwent PD at Kaifeng Central Hospital from January 2020 to December 2022 were enrolled in this study.After 6 months of treatment,chest CT was performed to calculate the CAC score.General information and clinical laboratory results were collected and analyzed statistically to identify the incidence of CAC and its risk factors.Results Among the 62 patients with DKD who underwent PD,22(35.48%)had CAC.Compared with the non-CAC group,the CAC group had a significantly higher age,P,PTH,and OPG levels(P<0.05).There were no significant differences in gender,smoking,BMI,SBP,DBP,CR,BUN,UA,HB,ALB,TC,TG,and Ca levels between the two groups(P>0.05).Binary logistic regression analysis showed that elevated P and OPG levels were independent risk factors for CAC.Conclusion In DKD patients newly on PD,higher levels of blood P and OPG are associated with an increased risk of CAC.

关 键 词：腹膜透析 冠状动脉钙化 危险因素 

分 类 号：R587.1[医药卫生—内分泌]