前列腺增生经尿道前列腺等离子切除术后夜尿症状改善的多因素分析  

Multivariate Analysis of Improvement of Nocturia Symptoms after Transurethral Plasma Resection of the Prostate in Patients with Prostatic Hyperplasia

作　　者：王欣欣 朱永敏[1] 刘艳华 WANG Xin-xin;ZHU Yong-min;LIU Yan-hua(Shangqiu First People's Hospital,Shangqiu 476000,Henan Province,China)

机构地区：[1]商丘市第一人民医院,河南商丘476000

出　　处：《罕少疾病杂志》2024年第11期88-90,共3页Journal of Rare and Uncommon Diseases

基　　金：河南省医学科技攻关计划(联合共建)项目(LHGJ20191004)。

摘　　要：目的本研究旨在探索经尿道前列腺等离子切除术(TUPKP)对前列腺增生患者夜尿症状改善的效果,以及影响术后疗效的相关因素。方法从2021年5月至2023年1月期间在我院就诊的前列腺增生患者100例中随机选取,分为对照组(50人)和观察组(50人)。对照组接受经尿道前列腺电切术,观察组则接受经尿道前列腺等离子电切术。比较两组术后前列腺特异性抗原(PSA)和最大尿流率等指标,并对比手术前后的国际前列腺症状评分(IPSS)、膀胱过度活动症状评分(OABSS)以及生活质量评分(QOL)。采用Logistic回归分析影响夜尿症状改善的相关因素。结果观察组患者术后PSA表达显著低于对照组,而最大尿流率则显著高于对照组;观察组患者术后的IPSS评分(包括尿频、尿急、夜尿次数、尿不尽感、排尿分段、尿线变细、排尿等待)均显著低于对照组;观察组患者术后OABSS评分显著低于对照组;观察组患者术后的生活质量评分则显著高于对照组;病程大于3年、OABSS评分过高以及采用经尿道前列腺电切术的患者夜尿症状风险增加。结论夜尿频繁是多种危险因素综合作用的结果,为前列腺增生患者实施TUPKP干预,能有效降低夜尿次数,改善排尿症状,从而提高患者生活质量。Objective The aim of this study is to explore the impact of transurethral plasmakinetic prostatectomy(TUPKP)on the improvement of nocturia symptoms in patients with benign prostatic hyperplasia,and to analyze factors affecting the postoperative efficacy.Methods A total of 100 patients with benign prostatic hyperplasia who visited our hospital from May 2021 to January 2023 were randomly divided into two groups:the control group(50 patients)who underwent transurethral prostatectomy,and the observation group(50 patients)who underwent transurethral plasmakinetic prostatectomy.The postoperative indices(PSA,maximum urinary flow rate)of all patients were compared,and the pre-and post-operative scores of International Prostate Symptom Score(IPSS),Overactive Bladder Symptom Score(OABSS),and Quality of Life score(QOL)were compared.Logistic regression analysis was used to analyze factors related to the improvement of nocturia symptoms.Results The postoperative PSA expression of the observation group was significantly lower than that of the control group,while the maximum urinary flow rate was significantly higher.The postoperative IPSS scores(including frequency,urgency,nocturia,incomplete emptying,intermittent urination,thin urine line,and waiting for urination)of the observation group were all significantly lower than those of the control group.The postoperative OABSS score of the observation group was significantly lower than that of the control group.The postoperative QOL score of the observation group was significantly higher than that of the control group.Patients with a disease course greater than 3 years,high OABSS scores,and transurethral resection of the prostate were at increased risk of nocturia symptoms.Conclusion Frequent nocturia is the result of a combination of multiple risk factors.Implementing TUPKP intervention for patients with benign prostatic hyperplasia can effectively reduce the number of nocturia,improve urination symptoms,and thus enhance the quality of life of patients.

关 键 词：前列腺增生 经尿道前列腺等离子切除术 夜尿症状改善 多因素分析 

分 类 号：R563.9[医药卫生—呼吸系统]