环境及生物样品中磁性微纳颗粒分析方法的研究进展  

Research Progress in Analytical Methods of Magnetic Micro/Nanoparticles in Environmental and Biological Samples

作　　者：刘琳 杨航 黄姹 刘倩[1,2] 江桂斌 LIU Lin;YANG Hang;HUANG Cha;LIU Qian;JIANG Gui-Bin(State Key Laboratory of Environmental Chemistry and Ecotoxicology,Research Center for Eco-Environmental Sciences,Chinese Academy of Sciences,Beijing 100085,China;College of Resources and Environment,University of Chinese Academy of Sciences,Beijing 100049,China)

机构地区：[1]中国科学院生态环境研究中心,环境化学与生态毒理学国家重点实验室,北京100085 [2]中国科学院大学资源与环境学院,北京100049

出　　处：《分析化学》2024年第10期1446-1456,共11页Chinese Journal of Analytical Chemistry

基　　金：国家自然科学基金项目(Nos.22425041,22188102)资助。

摘　　要：磁性颗粒(Magnetic particles,MPs)广泛存在于多种环境介质中,具有环境赋存浓度高和来源复杂等特性。近十年,随着MPs分离技术和检测方法的快速发展,关于人体内存在外源性MPs的报道层出不穷。其中,在人脑和血液中检测出MPs的报道引起了人们对健康风险的高度关注,尤其是MPs的赋存可能与阿尔兹海默病等神经退行性疾病的发生存在潜在关联。因此,对环境和生物介质中的MPs开展全面分析是理解其物理化学性质、了解其生物地球化学循环过程以及评估其环境和健康风险的重要基础。本文系统地总结了MPs在不同环境介质及生物体中的赋存情况,归纳了近年来MPs的分离手段、表征手段、定性及定量分析方法和溯源技术,并对MPs分析技术的未来发展前景进行了展望。Magnetic particles(MPs)are widely present in the environment,with high prevalence and complex sources.During the past decade,with the rapid development of separation techniques and detection methods for MPs,exogenous MPs have been found to be present in different parts of human body.Especially,the presence of MPs in human brain and blood has led to a high level of concern about their health risks,as the potential association with the development of neurodegenerative diseases such as Alzheimer′s disease.Therefore,analysis of MPs in environmental and biological media is an important basis for understanding their physicochemical properties,investigating their biogeochemical cycling processes,and assessing their environmental and health risks.Here,the occurrence of MPs in different environmental media and biological samples were systematically summarized.The separation methods,characterization methods,qualitative and quantitative analysis methods,and source apportionment techniques of MPs were also reviewed.Finally,the future challenges in the development of analytical techniques for MPs were discussed.

关 键 词：磁性颗粒 环境赋存 分离 环境样品 生物样品 评述 

分 类 号：O652[理学—分析化学] X830[理学—化学]