Cox-IMCHB在急性淋巴细胞白血病学龄前儿童口腔黏膜炎干预中的应用研究  

Application of intervention of oral mucositis based on Cox-IMCHB in preschool children with acute lymphoblastic leukemia

作　　者：刘纯子 张燕[1] 粱慧敏 张慧敏 解文君 王春梅[1] LIU Chunzi;ZHANG Yan;LIANG Huimin;ZHANG Huimin;XIE Wenjun;WANG Chunmei(School of Nursing,Tianjin Medical University,Tianjin 300070,China;Department of Pediatric Hematology/Oncology,State Key Laboratory of Experimental Hematology,National Clinical Research Center for Blood Diseases,Haihe Laboratory of Cell Ecosystem,Institute of Hematology&Blood Diseases Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Tianjin 300020,China;Tianjin Institutes of Health Science,Tianjin 301600,China)

机构地区：[1]天津医科大学护理学院,天津300070 [2]中国医学科学院血液病医院(中国医学科学院血液学研究所)儿童血液与肿瘤诊疗中心,血液与健康全国重点实验室,国家血液系统疾病临床医学研究中心,细胞生态海河实验室,天津300020 [3]天津医学健康研究院,天津301600

出　　处：《天津医科大学学报》2024年第6期548-553,共6页Journal of Tianjin Medical University

摘　　要：目的:探讨Cox健康行为互动模式(Cox-IMCHB)应用于急性淋巴细胞白血病(ALL)学龄前儿童口腔黏膜炎干预中的效果。方法:采用便利抽样法选取2023年1—12月于中国医学科学院血液病医院(中国医学科学院血液学研究所)进行化疗的50例ALL患儿,将其按照入院时间进行分组,2023年1—6月收治的患儿为对照组,2023年7—12月收治的患儿为研究组,各25例。对照组采取常规健康教育模式,研究组采取Cox-IMCHB的护理干预,比较两组口腔黏膜炎的发生率、严重程度、持续时间及患儿口腔治疗依从性和照顾者满意度调查表得分。结果:干预后,研究组患儿口腔黏膜炎发生率低于对照组(χ^(2)=5.433,P<0.05),口腔黏膜炎持续时间中位数为3.00(2.50,3.00)d,短于对照组[5.00(3.75,6.00)d(Z=-3.293,P<0.05)]。干预后,对照组患儿的口腔护理依从性低于研究组(Z=-3.906,P<0.001),对照组照顾者满意度调查表得分低于研究组(t=-15.127,P<0.001)。结论:基于Cox-IMCHB的干预方案可提高ALL学龄前儿童口腔治疗的依从性,降低口腔黏膜炎的发生率,缩短口腔黏膜炎的持续时间,提升照顾者满意度。Objective:To investigate the effect of the Cox interaction model of client health behavior(Cox-IMCHB)in the intervention of oral mucositis among preschool children with acute lymphoblastic leukemia(ALL).Methods:Using convenience sampling,50 children with ALL undergoing chemotherapy in Institute of Hematology&Blood Diseases Hospital of the Chinese Academy of Medical Sciences from January to December 2023 were selected and grouped according to their admission time.The control group comprised children admitted from January to June 2023,while the study group included children admitted from July to December 2023,with 25 children in each group.The control group received routine health education,while the study group received nursing interventions based on the Cox-IMCHB model.The incidence,severity,and duration of oral mucositis,oral treatment compliance,and caregiver satisfaction scores were compared between the two groups.Results:After the intervention,the incidence of oral mucositis in the study group was lower than that in the control group(χ^(2)=5.433,P<0.05).The median duration of oral mucositis was 3.00(2.50,3.00)days in the study group,shorter than that of 5.00(3.75,6.00)days in the control group(Z=-3.293,P<0.05).After the intervention,the oral care compliance of children in the control group was lower than that of the study group(Z=-3.906,P<0.001),and the caregiver satisfaction questionnaire score of the control group was lower than that of the study group(t=-15.127,P<0.001).Conclusion:The intervention program based on Cox-IMCHB can improve oral care compliance among preschool children with ALL,reduce the incidence of oral mucositis,shorten its duration,and enhance caregiver satisfaction.

关 键 词：急性淋巴细胞白血病 学龄前儿童 Cox健康行为互动模式 口腔黏膜炎 

分 类 号：R725.5[医药卫生—儿科]