Dual-physical network PVA hydrogel commensurate with articular cartilage bearing lubrication enabled by harnessing nanoscale crystalline domains  

作　　者：Danli Hu Desheng Liu Yue Hu Yixian Wang Yaozhong Lu Changcheng Bai Khan Rajib Hossain Pan Jiang Xiaolong Wang 

机构地区：[1]State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, China [2]Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing, 100049, China [3]Key Laboratory of Chemistry of Northwestern Plant Resources of Chinese Academy of Sciences, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, China [4]Shandong Laboratory of Advanced Materials and Green Manufacturing at Yantai, Yantai Zhongke Research Institute of Advanced Materials and Green Chemical Engineering, Yantai, 264006, China

出　　处：《Nano Research》2024年第11期9784-9795,共12页纳米研究（英文版）

基　　金：financial support from the National Key Research and Development Program of China(No.2022YFB4600101);the National Natural Science Foundation of China(Nos.52175201 and 52205228);the Science Fund of Shangdong Laboratory of Advanced Materials and Green Manufacturing at Yantai(No.AMGM2024F12);the Research Program of Science and Technology Department of Gansu Province(No.22JR5RA107);the Shandong Provincial Natural Science Foundation(No.ZR2023OE090);the Major Program(No.ZYFZFX-2);the Cooperation Foundation for Young Scholars(No.HZJJ23-02)of the Lanzhou Institute of Chemical Physics,CAS;the Taishan Scholars Program;the Special Research Assistant Project of the Chinese Academy of Sciences.

摘　　要：Hydrogel, as one of potential soft materials for articular cartilage, has encountered pressing obstacles, such as insufficient mechanical properties, poor lubrication, and easy to wear. To tackle these, we propose a strong yet slippery polyvinyl alcohol/chitosan (PVA/CS) hydrogel with dual-physically crosslinked networks by harnessing freeze-thawing, salting-out, annealing, and rehydration. High mechanical properties of PVA/CS hydrogel can be readily regulated by adjusting proportion of PVA/CS and annealing temperature. The optimized hydrogel exhibits high mechanical properties with tensile strength of ∼ 19 MPa at strain of 550%, compression strength of ∼ 11 MPa at small strain of 39%, and outstanding toughness and antifatigue owing to the robust physical interactions, including hydrogen bonds, crystallization, and ionic coordination. Moreover, the equilibrium hydrogel shows low friction coefficient of ∼ 0.05 against Al_(2)O_(3) ball under the condition of 30 N, 1 Hz, with water as the tribological medium, which is close to the lubrication performance of native cartilage. And meanwhile, the proposed cartilage-like slippery hydrogel displays stable long-term lubrication performance for 1 × 10^(5) reciprocating cycles without destructive wear and structure damage. It is therefore believed that the biocompatible cartilage-like slippery hydrogel opens innovative scenarios for developing cartilage-mimicking water-lubricated coating and biomedical implants with satisfactory load-bearing and lubrication performance.

关 键 词：slippery hydrogel bio-lubrication high load-bearing salting-out and annealing abrasion resistance 

分 类 号：TQ427.26[化学工程] R318[医药卫生—生物医学工程]