From“stars”to nano:Porous poly(ethylene glycol)hydrogel films and nanosheets as a versatile platform for sensing and nanofabrication  

作　　者：Michael Zharnikov 

机构地区：[1]Angewandte Physikalische Chemie, Universität Heidelberg, Im Neuenheimer Feld 253, D-69120, Heidelberg, Germany

出　　处：《Nano Research》2024年第11期10069-10082,共14页纳米研究（英文版）

基　　金：Funding note:Open Access funding enabled and organized by Projekt DEAL.

摘　　要：The use of bioinert materials is crucially important for medicine and bioengineering.The most popular systems in this context are oligo-and poly(ethylene glycols)(OEGs and PEGs),applied generally in different forms as bulk materials,thin films,and functional molecular groups.Here,I review the fabrication,properties,and applications of porous hydrogel PEG films(PHFs)and nanosheets(PHNs)formed by thermally activated crosslinking of amino-and epoxy-terminated,star-branched PEG oligomers with variable molecular weight.These systems possess various useful characteristics,including tunable thickness and porosity,hydrogel properties,bioinertness,robustness,and extreme elasticity.They can serve as the basis for composite materials,advanced nanofabrication,and lithography,bioinert supports for high-resolution transmission electron microscopy,susceptible elements in micro-electromechanical systems,and basic building blocks of temperature,humidity,chemical,and biological sensors.Representative examples of the respective applications are provided.Even though these examples span a broad field-from nanoengineering to biosensing,the applications of the PHFs and PHNs are certainly not limited to these cases but can be specifically adapted and extended to other fields,such as tissue engineering and drug delivery,relying on versatility and tunability of these systems.

关 键 词：poly(ethylene glycol) hydrogel films bioinertness NANOSHEETS sensors composite materials 

分 类 号：TP212[自动化与计算机技术—检测技术与自动化装置] TQ427.26[自动化与计算机技术—控制科学与工程] TB383[化学工程]