肠胶质细胞在维持肠道健康中的作用  

Role of enteric glial cells in maintaining intestinal health

作　　者：尹一茹 张为 杨晟曦 田卓佳 袁飞宇 程长安 吴建云[1] YIN Yiru;ZHANG Wei;YANG Shengxi;TIAN Zhuojia;YUAN Feiyu;CHENGG Changan;WU Jianyun(College of Veterinary Medicine,Southwest UUniversity,Beibei,Chongqing 400715,China)

机构地区：[1]西南大学动物医学院,重庆北碚400715

出　　处：《中国兽医学报》2024年第9期2081-2086,共6页Chinese Journal of Veterinary Science

基　　金：重庆市科学技术局资助项目(cstc2018jscx-mszd-X0048)。

摘　　要：肠胶质细胞(enteric glial cells,EGCs)作为肠神经系统(enteric nervous system,ENS)的重要组成部分,在调节人类及动物肠道稳态、维持肠道健康等方面发挥着重要作用。本试验主要就EGCs在维持肠道屏障稳态、维护胃肠传输及运动功能、调节肠道细胞生态位以及在肠道疾病发生发展中的作用等方面进行综述,为进一步研究EGCs在肠道中的功能、作用机制以及相关肠道疾病的发生、发展和治疗等提供新的思路。As an important part of the enteric nervous system(ENS),enteric glial cells(EGCs)play an important role in regulating intestinal homeostasis and maintaining intestinal health in humans and animals.This review focuses on the role of EGCs in maintaining intestinal barrier homeostasis,maintaining gastrointestinal transit and motor function,regulating the niche of intestinal cells,and the role in the occurrence and development of intestinal diseases,hoping to provide new ideas for further research on the function and mechanism of EGCs in the intestine and the occurrence,development and treatment of related intestinal diseases.

关 键 词：肠胶质细胞 肠神经系统 肠上皮屏障 肠道生态位 

分 类 号：S831.1[农业科学—畜牧学]