从气虚毒滞论治慢性溃疡  

Treating Chronic Ulcers from Perspective of“Qi Deficiency Toxic Stagnation”

作　　者：张秉睿 苏文全 王可彬 杜雅薇[1] 吴圣贤[1] ZHANG Bingrui;SU Wenquan;WANG Kebin;DU Yawei;WU Shengxian(Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China;Shunyi Hospital,Beijing Hospital of Traditional Chinese Medicine,Beijing 101399,China)

机构地区：[1]北京中医药大学东直门医院,北京100700 [2]北京中医医院顺义医院,北京101399

出　　处：《辽宁中医药大学学报》2024年第11期61-65,共5页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：国家科技重大专项-重大新药创制项目(2017ZX09304019)。

摘　　要：慢性溃疡既包括体表皮肤溃疡,又包括消化道内的慢性胃溃疡、慢性十二指肠溃疡、溃疡性结肠炎和血管内的动脉粥样硬化斑块溃疡等。气虚毒滞证是慢性溃疡特有的核心证候,“气虚”为慢性溃疡发病之本,包括热盛耗气、脾胃气虚、肾气亏虚,“毒滞”为慢性溃疡发病之标,包括热毒、痰毒、瘀毒之滞。临床见神疲、乏力等气虚的全身表现以及溃疡久不愈合、平坦塌陷的局部表现。治疗慢性溃疡气虚毒滞证以补气解毒为主,又根据脏腑归属、溃疡部位、溃疡形色的不同有所差异,其内服、外用方药各具特色。课题组提出以补气解毒作为治疗大法,自拟补气解毒汤为主方治疗,以期为临床治疗慢性溃疡气虚毒滞证提供系统思路和有效方法。Chronic ulcers include surface skin ulcers,chronic gastric ulcers,chronic duodenal ulcers,ulcerative colitis,atherosclerotic plaque ulcers and so on.Qi deficiency and toxic stagnation is the central and unique syndrome of chronic ulcers.Qi deficiency is the pathogenesis of chronic ulcers,including exuberant heat damaging Qi,spleen Qi deficiency and kidney Qi deficiency.Toxic stagnation is the manifestation of chronic ulcers,including stagnant of heat toxin,phlegm toxin and stasis toxin.The symptoms include fatigue,weakness and other systemic symptoms of Qi deficiency,with hard-healing and sunken ulcers.The treatment of Qi deficiency and toxic stagnation syndrome of chronic ulcers is based on tonifying Qi and removing toxins,which differs according to Zang-Fu belonging,location and appearance of ulcer.We devise Buqi Jiedu Decoction(补气解毒汤)as a primary treatment,in order to provide systematic ideas and effective methods for treating chronic ulcers of Qi deficiency and toxic stagnation.

关 键 词：慢性溃疡 气虚毒滞证 动脉粥样硬化 皮肤溃疡 补气解毒汤 

分 类 号：R268[医药卫生—中医外科学] R364.16[医药卫生—中医学]