鹰爪花属植物化学成分和生物活性的研究进展  

Research progress on chemical constituents and biological activities of Artabotrys plants

作　　者：赵培 刘水林 陈银 黄胜雄[2] ZHAO Pei;LIU Shui-lin;CHEN Yin;HUANG Sheng-xiong(Yinchuan Hospital of Traditional Chinese Medicine,Yinchuan 750001,China;State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650201,China;School of Ethnic Medicine,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,China)

机构地区：[1]银川市中医医院,银川750001 [2]中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,昆明650201 [3]成都中医药大学民族医药学院,成都611137

出　　处：《天然产物研究与开发》2024年第11期1972-1997,共26页Natural Product Research and Development

基　　金：2022年银川市学术技术带头人储备工程项目(2022-37);国家杰出青年科学基金(8222500537)。

摘　　要：鹰爪属植物在全球范围内现存100多种,在我国有4种,主要分布在南部,有悠久的药用历史,主要用于疟疾、风湿等顽疾。经现代药化学和药理学研究证实该属植物的化学成分种类多样,涉及十几个分类,主要有生物碱类、萜类、甾体类、环己烯类、黄酮类、醌类、苯丙素类及挥发油等,生物活性也十分丰富,具有抗肿瘤、抗菌、抗病毒、抗疟、抗虫、抗生育、抗凝血、抗血小板、抗氧化和细胞保护作用等。本文对其化学成分和生物活性进行详细综述,为其资源开发研究奠定了理论基础。There are more than 100 kinds of Artabotrys plants extant in the world.There are four species in China,which are mainly distributed in the south and people have a long medicinal history,mainly using it for malaria,rheumatism and other stubborn diseases.Modern pharmacochemical and pharmacological studies have confirmed that the chemical constituents of Artabotrys plants are diversified,involving more than a dozen categories,including alkaloids,terpenoids,cyclohexenes,steroids,flavonoids,quinones,phenylpropanes and volatile oils,etc.The biological activities of this genus are also very rich,with anti-tumor,antibacterial,antiviral,antimalarial,anti-insect,antifertility,antithrombin,antiplatelet,antioxidative,cytoprotection and so on.In this paper,the chemical constituents and biological activities of the plant were reviewed in detail,which laid a theoretical foundation for its resource development.

关 键 词：鹰爪属 阿朴菲 倍半萜 物质基础 生物活性 

分 类 号：R932[医药卫生—生药学]