烯肟菌胺中间体缩合酯的热安全性研究  

Thermal safety for condensed ester,a intermediate of fenaminstrobin

作　　者：于东锦 刘铁越 马晓华[3] 谭继爽 程春生 魏振云[3] 刘立志 YU Dongjin;LIU Tieyue;MA Xiaohua;TAN Jishuang;CHENG Chunsheng;WEI Zhenyun;LIU Lizhi(School of Materials Science and Engineering,Shenyang University of Technology,Shenyang 110870,China;School of Materials Science and Engineering,Shenyang University of Chemical Technology,Shenyang 110142,China;Chemical Industry Safety Technology&Engineering Center,Shenyang Research Institute of Chemical Industry,Shenyang 110021,China;Shenyang SCIENCREAT Chemicals Co.,Ltd.,Shenyang 110013,China)

机构地区：[1]沈阳工业大学材料科学与工程学院,沈阳110870 [2]沈阳化工大学材料科学与工程学院,沈阳110142 [3]沈阳化工研究院有限公司化工安全技术与工程中心,沈阳110021 [4]沈阳科创化学品有限公司,沈阳110013

出　　处：《农药》2024年第11期802-807,830,共7页Agrochemicals

基　　金：“十四五”国家重点研发计划(2021YFC3001101)。

摘　　要：[目的]缩合酯是合成创制杀菌剂烯肟菌胺的重要中间体。研究了缩合酯的热安全性,为企业生产过程安全提供科学依据。[方法]采用动态差示扫描量热,以及差示扫描量热和绝热加速量热联合测试技术,研究获取缩合酯的热稳定性及分解动力学参数。[结果]缩合酯具有热敏性,起始分解温度为198.01℃,分解放热量为1940 kJ/kg;分解动力学研究表明,缩合酯热分解最大反应速率到达时间为8、24 h,对应的温度TD8、TD24分别为161.5、147.5℃。[结论]缩合酯具有热不稳定性,分解过程放热剧烈,失控后果严重;应用2种模拟方法所获得的动力学结果具有很好的一致性。[Aims]Condensed ester is an important intermediate in the synthesis of the innovative fungicide fenaminstrobin.This research investigated the thermal safety of condensation ester to provide a scientific basis for ensuring the safety in the production process.[Methods]Dynamic differential scanning calorimetry(DSC)and a combination of DSC and adiabatic accelerating rate calorimetry(ARC)testing techniques were employed to study and obtain parameters related to the thermal stability and decomposition kinetics of condensed ester.[Results]Condensed ester exhibited thermal sensitivity,with an initial decomposition temperature of 198.01℃and a decomposition heat release of 1940 kJ/kg.Decomposition kinetics studies revealed that the thermal decomposition reaction rate of condensed esters reached its maximum at 8 and 24 h,corresponding to temperatures TD8 and TD24 of 161.5 and 147.5℃.[Conclusions]Condensed ester demonstrates thermal instability,with intense heat release during the decomposition process and severe consequences upon losing control.The kinetic results obtained from both simulation methods show good consistency.

关 键 词：烯肟菌胺 缩合酯 分解动力学 热安全性 

分 类 号：TQ450.11[化学工程—农药化工]