阻塞性睡眠呼吸暂停与新型冠状病毒关系的研究进展  

Advances in the relationship between obstructive sleep apnea and COVID-19

作　　者：彭裕 高怡青 许华俊[1,2] 李馨仪 刘玉璞 易红良[1,2] 关建 殷善开[1,2] PENG Yu;GAO Yiqing;XU Huajun;LI Xinyi;LIU Yupu;YI Hongliang;GUAN Jian;YIN Shankai(Department of Otolaryngology-Head and Neck Surgery,Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200233,China;Shanghai Key Laboratory of Sleep Disordered Breathing,Shanghai 200233,China)

机构地区：[1]上海交通大学医学院附属第六人民医院耳鼻咽喉头颈外科,上海200233 [2]上海市睡眠呼吸障碍疾病重点实验室,上海200233

出　　处：《中国眼耳鼻喉科杂志》2024年第6期487-492,共6页Chinese Journal of Ophthalmology and Otorhinolaryngology

基　　金：科技创新2030(2021ZD0201900);上海市科学技术委员会科技创新行动计划(18DZ2260200);上海申康医院发展中心促进市级医院临床技能与临床创新三年行动计划(SHDC2020CR2044B,SHDC2020CR3056B)。

摘　　要：新型冠状病毒感染(coronavirus disease 2019,COVID-19)因其高传播性、高病死率引发全球的大流行,造成重大社会损失和医疗负担,引起广泛关注。已有多篇文章分析了COVID-19患者的临床特点,发现其不良预后与其同时罹患高血压、糖尿病、心血管疾病和肥胖等慢性疾病密切相关。阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)是最常见的睡眠呼吸障碍疾病之一,也与上述慢性疾病关系极其密切。同时,OSA在重症COVID-19患者中比例较高,且多项研究证实了OSA对COVID-19患者的预后存在不良影响。本综述主要探讨OSA与COVID-19的相互关系,及在COVID-19疫情流行的形势对OSA诊治的影响。Coronavirus disease 2019(COVID-19)has caused a global pandemic with significant social losses and medical burden due to its high transmissibility,high morbidity and mortality rates,which has caused widespread concern.Several articles have analyzed the clinical characteristics of patients with COVID-19 infection and found that their poor prognosis is closely related to the presence of chronic diseases such as hypertension,diabetes,cardiovascular disease and obesity.Obstructive sleep apnea(OSA)is one of the most common sleep apnea disorders and is also very closely related to these chronic diseases.At the same time,OSA has a high prevalence in patients with severe COVID-19 infection and several studies have confirmed the adverse effect of OSA on the prognosis of patients with COVID-19 infection.This review focused on the interrelationship between OSA and COVID-19 and the impact on the management of OSA in an epidemic situation.

关 键 词：阻塞性睡眠呼吸暂停 新型冠状病毒感染 病理生理 诊断 治疗 

分 类 号：R764.21[医药卫生—耳鼻咽喉科]