育龄女性原发性及继发性不孕症影响因素分析  

Analysis of the influencing factors of the primary and the secondary infertility of women of childbearing age

作　　者：张丽[1] 卫小静 彭爱萍 杨芳芳 ZHANG Li;WEI Xiaojing;PENG Aiping;YANG Fangfang(Linfen People's Hospital,Linfen,Shanxi Province,041000)

机构地区：[1]山西省临汾市人民医院,041000

出　　处：《中国计划生育学杂志》2024年第11期2493-2497,共5页Chinese Journal of Family Planning

摘　　要：目的:调查育龄女性原发性与继发性不孕症的发生情况并分析相关影响因素。方法:选取2022年1月-2024年1月在本院生殖中心就诊的育龄不孕症女性602例(不孕组)和正常妊娠女性(对照组)602例为研究对象,发放调查问卷进行调查,对比不孕症患者与对照组临床资料,logistic回归影响原发性不孕和继发性不孕的相关因素。结果:不孕组中原发性不孕症患者体质指数(BMI)≥25kg/m^(2)、月经失调、生殖发育异常、多囊卵巢综合征(PCOS)、黄体功能不全、高泌乳血症、子宫内膜异位症占比高于对照组,继发性不孕患者BMI≥25kg/m^(2)、月经失调、经常失眠、生殖道感染、子宫内膜异位症、宫腔手术史占比高于对照组(均P<0.05)。多因素分析显示,BMI≥25kg/m^(2)、月经失调、生殖系统发育异常、PCOS、高泌乳血症、子宫内膜异位症为原发性不孕的危险因素,月经失调、经常失眠、生殖道感染、子宫内膜异位症、宫腔手术史为继发性不孕的危险因素(均P<0.05)。结论:育龄不孕症女性中继发性不孕构成比高于原发性不孕,且二者危险因素差异较大,前者的发生与月经失调、失眠、生殖道感染、宫腔手术史等相关性较强,后者则与超重/肥胖、先天生殖发育异常、PCOS等有更强的相关性。Objective:To investigate the incidence of the primary and secondary infertility of women of childbearing age,and to analyze the relevant influencing factors of the primary and the secondary infertility of the women.Methods:602 infertile women of childbearing age(in study group)who visited the reproductive center of the hospital from January 2022 to January 2024 and 602 normal pregnant women(in control group)during the same period were selected as the study subjects.The questionnaires were distributed for investigation.The clinical data of the women were compared between the two groups.Logistic regression analysis was used to analyze the relevant factors affecting the primary and the secondary infertility of the women.Results:The proportions of the body mass index(BMI)≥25kg/m^(2),the menstrual disorder,the reproductive abnormalities,the polycystic ovary syndrome(PCOS),the corpus luteum insufficiency,the hyperprolactinemia and the endometriosis of the women with the primary infertility in the study group were significantly higher than those of the women in the control group.The proportions of BMI≥25kg/m^(2),the menstrual disorder,the frequent insomnia,the reproductive tract infection,the endometriosis and the history of uterine surgery of the women with the secondary infertility in the study group were significantly higher than those of the women in the control group(all P<0.05).Multivariate analysis showed that BMI≥25kg/m^(2),the menstrual disorder,the reproductive dysplasia,PCOS,the hyperprolactinemia and the endometriosis of the women were the risk factors of their primary infertility,and the menstrual disorder,the frequent insomnia,the reproductive tract infection,the endometriosis and the history of intrauterine surgery of the women were the risk factors of their secondary infertility(all P<0.05).Conclusion:The proportion of the secondary infertility of the infertile women of reproductive age is higher than that of the primary infertility.There is significant difference in the risk factors between the wo

关 键 词：育龄女性 原发性不孕症 继发性不孕症 影响因素 

分 类 号：R711.6[医药卫生—妇产科学]