1041例肾脏疾病患者的肾组织活检病理分析  

Pathological analysis of renal tissue biopsy in 1041 patients with renal disease

作　　者：邱杨媚 张庆宇 鄢雨纯 颜晓勇 Qiu Yangmei;Zhang Qingyu;Yan Yuchun;Yan Xiaoyong(Department of Nephrology,Affiliated Hospital of Zunyi Medical University,Zunyi Guizhou 563000,China;Department of Clinical College,Zunyi Medical University,Zunyi Guizhou 563000,China)

机构地区：[1]遵义医科大学附属医院肾内科,贵州遵义563000 [2]遵义医科大学临床学院,贵州遵义563000

出　　处：《遵义医科大学学报》2024年第11期1082-1087,共6页Journal of Zunyi Medical University

摘　　要：目的分析1041例肾脏疾病患者的肾穿刺活检病理类型分布特点。方法回顾性选取1041例患者肾穿刺活检病理检查结果。按照时间段分为A组(2018年1月1日~2020年12月31日)、B组(2021年1月1日~2023年12月31日)。分析患者临床资料特点及病理类型变化。结果1041例研究对象中接受肾活检的多为青年(37.9%)、中年患者(39.8%)。原发性肾小球疾病(PGD)有808例(77.6%),主要病理类型为IgA肾病(IgAN)329例(40.7%),其次为膜性肾病(MN)224例(27.7%)、微小病变型肾病(MCD)172例(21.3%)。继发性肾小球疾病(SGD),主要病理类型为LN 93例(8.9%)、HSPN 32例(3.0%)、DN 26例(2.5%)、HTN24例(2.3%)。PGD中,B组中MN检出率较A组高;在SGD中,B组中HTN、DN检出率较A组高。结论本单中心研究对象主要以青、中年人为主,病理类型以PGD最为常见,其中以IgAN和MN为主。SGD病理类型以LN、HSPN、DN、HTN为主。随着时间变化,MN、HTN、DN逐渐增多。Objective The pathological types of renal biopsy in 1041 patients with renal disease were analyzed.Methods The data of 1041 patients with renal biopsy were retrospectively analyzed and statistically analyzed.There were divided into Group A(from January 1,2018 to December 31,2020)and Group B(from January 1,2021 to December 31,2023).Results Among the 1041 subjects,most of them were young(37.9%)and middle aged(39.8%).There were 808 cases(77.6%)of primary glomerular disease,the main pathological type was IgA nephropathy in 329 cases(40.7%),followed by membranous nephropathy in 224 cases(27.7%)and micropathological nephropathy in 172 cases(21.3%).There were 218 cases(20.9%)of secondary glomerular disease.The main pathologic types were lupus nephritis in 93 cases(8.9%),HSPN in 32 cases(3.0%),diabetic nephropathy in 26 cases(2.5%)and hypertensive nephropathy in 24 cases (2.3%).In PGD,the MN detection rate in group B was higher than that in group A.In SGD,the detection rate of HTN and DN in group B was higher than that in group A.Conclusion The subjects of this single-center study were mainly young and middle-aged people,and PGD was the most common pathological type,among which IgAN and MN were the main ones.The main pathologic types of SGD were LN,HSPN,DN and HTN.With the change of time,MN,HTN and DN was gradually increased.

关 键 词：肾脏病 肾穿刺活检 病理类型 回顾性分析 

分 类 号：R692.6[医药卫生—泌尿科学]