苏子降气汤加减治疗慢阻肺急性加重期患者的效果研究  

Study on the effect of modified Suzi Jiangqi Tang on patients with acute exacerbation of chronic obstructive pulmonary disease

作　　者：李大庆 LI Da-qing(Ganyu District Hospital of Traditional Chinese Medicine,Lianyungang 222100,China)

机构地区：[1]连云港市赣榆区中医院,222100

出　　处：《中国现代药物应用》2024年第21期140-143,共4页Chinese Journal of Modern Drug Application

摘　　要：目的分析慢阻肺急性加重期患者治疗中应用苏子降气汤加减的疗效。方法选取慢阻肺急性加重期患者100例作为研究对象,按全盲抓阄法分为两组,即对照组(50例,常规西医治疗)与观察组(50例,西医治疗+苏子降气汤加减治疗)。比较两组治疗前后生命体征指标、炎性指标、血气指标及临床疗效、不良反应发生情况。结果治疗后,观察组心率、呼吸频率、体温明显低于对照组(P<0.05)。治疗后,观察组白细胞计数(WBC)为(8±2)×10^(9)/L、C反应蛋白(CRP)为(6±1)mg/L、动脉血二氧化碳分压(PaCO_(2))为(47±4)mm Hg(1 mm Hg=0.133 kPa)、酸碱度(pH)值为(7.28±1.00)、动脉血氧分压(PaO_(2))为(64±6)mm Hg,对照组WBC为(11±3)×10^(9)/L、CRP为(8±2)mg/L、PaCO_(2)为(53±4)mm Hg、pH值为(6.85±1.00)、PaO_(2)为(55±6)mm Hg;治疗后,两组在WBC、CRP、PaCO_(2)、pH值、PaO_(2)等方面对比,观察组优于对照组(P<0.05)。观察组总有效率98.00%高于对照组的82.00%(P<0.05)。观察组不良反应发生率4.00%明显较对照组的16.00%低(P<0.05)。结论对慢阻肺急性加重期患者采取苏子降气加减治疗,能够使患者的生命体征恢复正常,并有效改善炎性指标、血气指标,提升治疗效果,且不良反应较少。Objective To analyze the curative effect of modified Suzi Jiangqi Tang on patients with acute exacerbation of chronic obstructive pulmonary disease.Methods 100 patients with acute exacerbation of chronic obstructive pulmonary disease were selected as study subjects,and were divided into two groups according to the double-blind lottery method,i.e.,the control group(50 cases,conventional Western medical treatment)and the observation group(50 cases,Western medical treatment+modified Suzi Jiangqi Tang treatment).The vital signs,inflammatory indicators and blood gas indicators before and after treatment,clinical efficacy,and occurrence of adverse reactions were compared between the two groups.Results After treatment,the heart rate,respiratory rate,and body temperature of the observation group were significantly lower than those of the control group(P<0.05).After treatment,the white blood cell count(WBC)of the observation group was(8±2)×10^(9)/L,the C-reactive protein(CRP)was(6±1)mg/L,the arterial partial pressure of carbon dioxide(PaCO_(2))was(47±4)mm Hg(1 mm Hg=0.133 kPa),the pH value was(7.28±1.00),and the arterial partial pressure of oxygen(PaO_(2))was(64±6)mm Hg,while in the control group,the WBC was(11±3)×10^(9)/L,the CRP was(8±3)mg/L,the PaCO_(2) was(53±4)mm Hg,the pH value was(6.85±1.00),and the PaO_(2) was(55±6)mm Hg.After treatment,both group were compared in terms of WBC,CRP,PaCO_(2),pH and PaO_(2),and the observation group was better than the control group(P<0.05).The total effective rate of 98.00%in the observation group was higher than 82.00%in the control group(P<0.05).The incidence of adverse reactions of 4.00%in the observation group was significantly lower than 16.00%in the control group(P<0.05).Conclusion Modified Suzi Jiangqi Tang can restore the vital signs of patients with acute exacerbation of chronic obstructive pulmonary disease to normal,effectively improve the inflammatory indicators and blood gas indicators,enhance the therapeutic effect,and has fewer adverse reactions.

关 键 词：苏子降气汤 慢性阻塞性肺疾病 急性加重期 炎性因子 

分 类 号：R259[医药卫生—中西医结合]