多模态MRI定量评估骨骼肌的研究进展  

Research progress in quantitative assessment by multimodal MRI in skeletal muscle

作　　者：张新茹 张晓东(审校) ZHANG Xinru;ZHANG Xiaodong(Department of Medical Imaging,The Third Affiliated Hospital,Southern Medical University(Academy of Orthopedics Guangdong Province),Guangzhou 510630,China)

机构地区：[1]南方医科大学第三附属医院(广东省骨科研究院)医学影像科,广州510630

出　　处：《国际医学放射学杂志》2024年第6期725-729,735,共6页International Journal of Medical Radiology

基　　金：广东省基础与应用基础研究基金自然科学基金(2024A1515010352)。

摘　　要：骨骼肌是骨骼-肌肉系统的重要组成部分,其解剖结构存在差异,病理生理状态的改变对于运动及骨骼肌疾病的治疗、预后都具有重要意义。概述骨骼肌形态学和组织学MRI定量参数(如骨骼肌横截面积、脂肪含量、炎性水肿状态、肌纤维结构类型)的评估方法及其临床应用,以及骨骼肌健康或疾病状态与MRI定量参数的相关性。就多模态MRI定量评估骨骼肌结构及功能的研究进展予以综述,并对其临床应用前景进行展望。Skeletal muscle,as an important component of the skeletal-muscular system,exhibits unique anatomical and structural characteristics.Pathophysiological changes in skeletal muscle are critical to movement,treatment approaches,and prognosis of skeletal muscle diseases.This review provides an overview of MRI-based quantitative parameters used to assess skeletal muscle morphology and histology(such as cross-sectional area,fat content,inflammatory edema status,and muscle fiber structure types),their assessment methods,and clinical applications,as well as the correlation between skeletal muscle health or disease states and MRI-derived quantitative parameters.Additionally,the review highlights recent advances in multimodal MRI for the quantitative evaluation of skeletal muscle structure and function,offering insights into potential clinical applications.

关 键 词：骨骼肌 磁共振成像 定量磁共振成像 骨骼肌功能 

分 类 号：R68[医药卫生—骨科学] R445.2[医药卫生—外科学]