心脏自主神经节消融在心房颤动消融中的价值  

The value of ganglionated plexi ablation in the atrial fibrillation ablation

作　　者：朱莉 郑黎晖 胡锋 ZHU Li;HU Feng;ZHENG Li-hui(Premium Care Department,Fuwai Hospital,Chinese Academy of Medical Sciences,Beijing 100037,China;Arrhythmia Center,Fuwai Hospital,Chinese Academy of Medical Sciences,Beijing 100037,China;Department of Cardiology,Renji Hospital,School of Medicine,Shanghai Jiaotong University,Shanghai 200127,China)

机构地区：[1]中国医学科学院阜外医院特需门诊,北京市100037 [2]中国医学科学院阜外医院心律失常中心 [3]上海交通大学医学院附属仁济医院心内科

出　　处：《中国心血管病研究》2024年第11期967-972,共6页Chinese Journal of Cardiovascular Research

基　　金：国家自然科学基金面上项目(82371595);中国医学科学院临床与转化医学研究专项(2022-I2M-C&T-B-045);中国医学科学院阜外医院高水平医院临床科研业务费(2022-GSP-QZ-4);中国医学科学院中央级公益性科研院所基本科研业务费(2022-RW320-11)。

摘　　要：心脏自主神经系统通过心脏神经节调控心房颤动(房颤)的发生和发展,但心脏神经节(GP)消融治疗房颤的临床疗效有待明确。同时,GP在房颤环肺静脉隔离术(CPVI)中的迷走神经反射发挥关键作用,消融右前GP能抑制房颤消融术中的迷走神经反射,改善房颤消融手术的安全性和手术效率。GP消融对于房颤合并的缓慢心律失常具有较为明确的获益。GP消融的远期疗效有待于进一步研究。Intrinsic cardiac autonomic nervous system via ganglionated plexi(GP)participates in regulating the development of atrial fibrillation(AF).However,the clinical efficacy of GP ablation remains to be determined.The GP is the critical structure for vagus reflex during circumferential pulmonary vein isolation(CPVI)for AF.Ablation of right anterior GP can inhibit the vagus reflex during CPVI procedure,thus helping to improve the safety and efficiency of CPVI for the AF.Ablation of GP also helps to improve the outcome of AF with bradycardia.The long-term efficacy of GP ablation remains to be determined.

关 键 词：心房颤动 心脏神经节 内源性自主神经系统 

分 类 号：R541.7[医药卫生—心血管疾病]