基于深度学习重建和传统TSE序列在直肠癌磁共振检查的对比研究  

Study on the value of deep reconstruction technique in improving the image quality of magnetic resonance rectal cancer

作　　者：胡思洁 范文文 滕泽 刘侃 童晓婉 江岳娈 刘鹏 郎宇 Nickel Marcel Dominik 张红梅 HU Sijie;FAN Wenwen;TENG Ze;LIU Kan;TONG Xiaowan;JIANG Yueluan;LIU Peng;LANG Yu;NICKEL MarcelDominik;ZHANG Hongmei(Department of Diagnostic Radiology,National Cancer Center,National Clinical Research Center for Cancer,Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China;Beijing Branch,Siemens Healthineers Ltd.,Beijing 100176,China;Siemens Healthineers AG,Erlangen,Germany)

机构地区：[1]国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院影像诊断科,北京100021 [2]西门子医疗系统有限公司北京分公司,北京100102 [3]西门子医疗系统有限公司,埃尔兰根,德国

出　　处：《磁共振成像》2024年第10期30-35,共6页Chinese Journal of Magnetic Resonance Imaging

摘　　要：目的评估深度学习重建(deep learning reconstruction,DL Recon)技术在提高直肠MRI快速自旋回波序列(turbo spin-echo,TSE)图像质量的价值。材料与方法前瞻性纳入2023年9月至2024年1月中国医学科学院肿瘤医院病理诊断为直肠癌的初诊患者60例,对每位患者进行临床传统TSE序列及应用DL Recon技术的TSE序列(deep learning reconstruction-TSE,DL-TSE)扫描,并记录扫描时间,由两名影像科医师分别对两组图像(传统TSE、DL-TSE)的图像质量进行主观评价,采用“五分法”分别对病灶轮廓清晰度,图像伪影,病灶结构清晰度以及诊断信心进行评分;由两名影像科技师进行客观评价,分别计算DL-TSE和传统TSE图像的病灶信噪比(signal-to-noiseratio,SNR)以及病灶区域与周边组织的对比噪声比(contrast-to-noise ratio,CNR),采用配对样本t检验或配对样本非参数检验(Wilcoxon符号轶检验)进行统计学分析。结果图像主观评价显示DL-TSE序列的病灶轮廓清晰度、图像伪影、病灶结构清晰度以及诊断信心的主观评分得分均优于传统TSE序列,且差异具有统计学意义(P<0.001)。图像客观评价显示DL-TSE序列和传统TSE序列的SNR分别为24.26(15.95,42.79)、11.84(7.63,18.88),差异有统计学意义(Z=-14.276,P<0.001);DL-TSE序列和传统TSE序列CNR分别为10.75(7.19,15.63),5.47(3.72,8.86),且差异有统计学意义(Z=-14.271,P<0.001)。DL-TSE序列的SNR及CNR相较于传统TSE序列均有明显提升。结论DL-TSE序列通过采用原始K空间数据DL Recon算法,在保证图像质量和病变可检测性的情况下,可提升直肠癌患者序列图像SNR及CNR,并且可缩短36.6%扫描时间。Objective:To evaluate the value of deep learning reconstruction(DL Recon)technique in improving the image quality of rectal MRI turbo spin-echo(TSE)sequences.Materials and Methods:Sixty new cases of rectal cancer diagnosed by pathology in the Chinese Academy of Medical Sciences from September 2023 to January 2024 were studied retrospectively.Each patient was subjected to a conventional TSE sequence and DL-TSE sequence,and the scanning time was recorded.Two imaging doctors had subjective evaluation for the two groups(conventional TSE,DL-TSE).The"five-point method"was used to score lesion contour clarity,the image artifacts,the clarity of the lesion and the reliability of the diagnosis,and the statistical description of the results was performed using the quartile interval M(Q25,Q75).The signal-to-noise ratio(SNR)and contrast-to-noise ratio(CNR)between the DL-TSE and the conventional TSE images were computed by two imaging technicians.Paired sample t test was used for statistical analysis of the data conforming to normal distribution,and paired sample non-parametric test(Wilcoxon symbolic significance test)was used for statistical analysis of the data not conforming to normal distribution,and the results were statistically described by the quartile interval M(Q25,Q75).Results:Sixty cases of rectal carcinoma aged 35-69(53±10)years old were enrolled.The subjective evaluation results of conventional TSE sequences and DL-TSE sequences:The focal contour clarity,image artifacts,focal structure clarity and subjective score of diagnostic confidence of DL-TSE sequence were better than those of traditional TSE sequence,and the differences were statistically significant(P<0.001).Objective evaluation results of traditional TSE sequence and DL-TSE sequence images:The SNR of DL-TSE and conventional TSE sequences were 24.26(15.95,42.79)and 11.84(7.63,18.88).The CNR of DL-TSE and conventional TSE sequences were 10.75(7.19,15.63)and 5.47(3.72,8.86),the difference was statistically significant(Z=−14.271,P<0.001).The SNR and the C

关 键 词：直肠癌 信噪比 对比噪声比 深度学习重建 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R735.37[医药卫生—诊断学]