湖南省新冠病毒再感染情况及其影响因素分析  

Prevalence of SARS-CoV-2 re-infection and its influencing factors in Hunan Province

作　　者：李孝君 蒋子豪 孙倩莱[1] 戴志辉 杨浩[1] 赵善露 LI Xiaojun;JIANG Zihao;SUN Qianlai;DAI Zhihui;YANG Hao;ZHAO Shanlu(Hunan Provincial Center for Disease Control and Prevention/Hunan Academy of Preventive Medicine,Changsha,Hunan 410153,China;Linxiang Center for Disease Control and Prevention,Yueyang,Hunan 414300,China)

机构地区：[1]湖南省疾病预防控制中心(湖南省预防医学科学院),湖南长沙410153 [2]临湘市疾病预防控制中心,湖南岳阳414300

出　　处：《实用预防医学》2024年第10期1172-1175,共4页Practical Preventive Medicine

基　　金：湖南省科学技术厅重点领域研发计划抗击新冠感染疫情应急专题项目(2022SK2121);湖南省卫生健康委员会科研计划项目(D202312058730);湖南省疾控中心青荷项目(QHJJ2023012)。

摘　　要：目的分析湖南省居民新冠病毒再感染情况及其影响因素,为再感染防控政策的制定提供数据支持。方法2023年6月依托湖南省传染病精密智控平台面向湖南省城市、农村居民开展线上问卷调查,采用χ^(2)检验和logistic回归分析发生再感染的影响因素。结果本次调查共纳入10983名既往感染者,其中2603名再感染者,新冠病毒再感染率为23.70%(95%CI:22.90%~24.50%);城市和农村再感染率分别为25.47%(95%CI:24.45%~26.50%)、20.68%(95%CI:19.44%~21.93%)。78.99%(2056/2603)再感染者感觉症状较上次感染更轻。多因素logistic回归分析结果显示居住在人口聚集地(OR=6.09,95%CI:5.08~7.29)、医务人员(OR=1.88,95%CI:1.68~2.11)更容易发生再感染,0~17岁(OR=0.31,95%CI:0.26~0.36)、≥60岁人群(OR=0.64,95%CI:0.62~0.79)较18~59岁年龄组更不容易发生再感染。结论部分新冠病毒感染者会出现再感染,其中大部分症状较首次感染轻,城市居民、医务人员、青壮年人群更容易发生再感染,建议在新冠病毒感染流行前期要做好重点人群的防控工作。Objective To analyze the status of SARS-CoV-2 re-infection and its influencing factors among residents in Hunan Province,and to provide data support for formulating the re-infection prevention and control policies.Methods In June 2023,an online questionnaire survey was conducted among urban and rural residents in Hunan Province based on the Precision Intelligent Control Platform for infectious diseases in Hunan Province.χ2 test and logistic regression were used to analyze the factors influencing the occurrence of re-infection.Results A total of 10,983 previously infected persons were included in this survey,and 2,603 of whom were re-infected,with the SARS-CoV-2 re-infection rate of 23.70%(95%CI:22.90%-24.50%).The re-infection rates of the urban and rural areas were 25.47%(95%CI:24.45%-26.50%)and 20.68%(95%CI:19.44%-21.93%)respectively.78.99%(2,056/2,603)of the re-infected persons felt that their symptoms were milder than those of the last infection.The results of multifactor logistic regression analysis displayed that living in the heavily populated area(OR=6.09,95%CI:5.08-7.29)and medical professionals(OR=1.88,95%CI:1.68-2.11)were more likely to be re-infected,and the groups aged 0-17 years(OR=0.31,95%CI:0.26-0.36)and 60 years and above(OR=0.64,95%CI:0.62-0.79)were less likely to had re-infection compared with the group aged 18-59 years.Conclusion Re-infection may occur in patients with previous SARS-CoV-2 infection,and the symptoms of most patients with re-infection are milder than those of patients with first infection.Urban residents,medical professionals and the young and middle-aged group are more likely to be re-infected,suggesting that re-infection prevention and control based on key populations should be done in the early stage of the SARS-CoV-2 pandemic.

关 键 词：新冠病毒 再感染 影响因素 

分 类 号：R563.1[医药卫生—呼吸系统]