诸暨市健康体检儿童手足口病隐性感染情况调查及影响因素探讨  

Prevalence of latent infection of hand,foot and mouth disease and its influencing factors among children undergoing physical examination in Zhuji City

作　　者：孟利青 屠苗英 斯琼 MENG Liqing;TU Miaoying;SI Qiong(Zhuji Municipal Maternal and Child Health Care Hospital,Zhuji,Zhejiang 311800,China;The Second People’s Hospital of Zhuji City,Zhuji,Zhejiang 311800,China)

机构地区：[1]诸暨市妇幼保健院,浙江诸暨311800 [2]诸暨市第二人民医院,浙江诸暨311800

出　　处：《实用预防医学》2024年第10期1200-1203,共4页Practical Preventive Medicine

摘　　要：目的分析诸暨市健康体检儿童手足口病(hand,foot and mouth disease,HFMD)隐性感染情况,并探讨相关影响因素,为诸暨市儿童HFMD防治工作的开展提供参考。方法选取2022年1—12月期间在诸暨市妇幼保健院体检的健康儿童526例,采集儿童肛拭子标本,采用荧光定量PCR法测定HFMD隐性感染情况。采用自制的调查问卷调查儿童的一般情况及相关家庭资料,分析影响儿童HFMD隐性感染的危险因素。结果526例健康体检儿童HFMD隐性感染率为27.95%。HFMD隐性感染儿童的年龄以0~3岁为主(占65.99%),性别比例分布较为均匀,感染时间主要发生于4—6月(占39.46%)。隐性感染组年龄≤3岁、父母对HFMD知识掌握不足、近1月内HFMD患者接触史、不良卫生习惯、无玩具清洁消毒习惯及每周体育运动时间≤3 h的比例高于未感染组,差异均有统计学意义(P<0.05)。多因素logistic回归分析显示,年龄≤3岁(OR=1.292,95%CI:1.023~1.631)、父母对HFMD知识掌握情况不足(OR=2.392,95%CI:1.277~4.478)、近1月内HFMD患者接触史(OR=1.650,95%CI:1.070~2.545)、不良卫生习惯(OR=1.156,95%CI:1.007~1.406)是HFMD隐性感染的影响因素(P<0.05)。结论诸暨市健康体检儿童HFMD隐性感染率较高,年龄≤3岁、父母对HFMD知识掌握情况不足、近1月内HFMD患者接触史、不良卫生习惯是HFMD隐性感染的独立危险因素。HFMD的防控工作中应重点关注3岁以内儿童,加强对儿童父母HFMD知识的宣教工作。Objective To analyze the recessive infection status of hand,foot and mouth disease(HFMD)among children undergoing physical examination in Zhuji City,to explore the related influencing factors,and to provide references for performing HFMD prevention and control in children in Zhuji City.Methods Anal swab samples were collected from 526 children who underwent physical examination in Zhuji Municipal Maternal and Child Health Care Hospital in January-December 2022,and the recessive infection of HFMD was determined by fluorescent quantitative PCR.A self-made questionnaire was used to investigate the children’s general information and related family data,and the risk factors affecting the latent infection of HFMD in the children were analyzed.Results The recessive infection rate of HFMD in the children undergoing physical examination was 27.95%.The age of children with HFMD recessive infection mainly ranged from 0 to 3 years old(accounting for 65.99%),and the sex ratio distribution was relatively uniform,mainly occurring in April-June(accounting for 39.46%).The proportions of≤3 years of age,parents’insufficient knowledge of HFMD,having a history of contact with HFMD patients in the last one month,having poor hygiene habits,having no toy cleaning and disinfection habits,and weekly exercise time≤3 hours were all higher in the recessive infection group than in the uninfected group,and the differences were statistically significant(all P<0.05).Multifactor logistic regression analysis revealed that≤3 years of age(OR=1.292,95%CI:1.023-1.631),parents’insufficient knowledge of HFMD(OR=2.392,95%CI:1.277-4.478),having a history of contact with HFMD patients in the last one month(OR=1.650,95%CI:1.070-2.545)and having poor hygiene habits(OR=1.156,95%CI:1.007-1.406)were factors affecting HFMD latent infection(P<0.05).Conclusion The recessive infection rate of HFMD in the children undergoing physical examination in Zhuji City is high.≤3 years of age,parents’insufficient knowledge of HFMD,having a history of contact w

关 键 词：手足口病 隐性感染 肠道病毒 影响因素 

分 类 号：R729[医药卫生—儿科]