奥硝唑注射液联合拉氧头孢钠治疗慢性盆腔炎的疗效及对血清炎症指标的影响  

Efficacy of Ornidazole Injection Combined with Latamoxef Sodium in the Treatment of Chronic Pelvic Inflammatory Disease and Its Effect on Serum Inflammatory Indicators

作　　者：王利勤 吴辰 WANG Li-qin;WU Chen(Fushan Community Health Service Center of Xianan District,Xianning Hubei 437100,China)

机构地区：[1]咸宁市咸安区浮山社区卫生服务中心,湖北咸宁437100 [2]咸宁市中心医院/湖北科技学院附属第一医院

出　　处：《湖北科技学院学报（医学版）》2024年第6期511-513,518,共4页Journal of Hubei University of Science and Technology(Medical Sciences)

摘　　要：目的探讨奥硝唑注射液联合拉氧头孢钠对慢性盆腔炎的临床治疗效果。方法将就诊于本院的慢性盆腔炎患者96例作为研究对象,随机分为对照组和观察组各48例。对照组给予拉氧头孢钠治疗,观察组给予奥硝唑联合拉氧头孢钠治疗。10d后,评价两组治疗效果,以及治疗前后盆腔积液量、临床症状评分和血清炎症指标水平差异,并观察不良反应。结果观察组总有效率93.75%显著高于对照组77.08%(P<0.05)。治疗后,与治疗前相比,两组盆腔积液量、症状评分均显著下降(P均<0.05);与对照组相比,观察组盆腔积液量、症状评分更低,差异具有显著性(P均<0.05)。治疗后,观察组白细胞计数、降钙素原和C反应蛋白水平显著低于对照组(P<0.05)。两组不良反应发生率不具有统计学差异(P>0.05)。结论奥硝唑注射液联合拉氧头孢钠对慢性盆腔炎有较好治疗效果,可更有效地降低机体炎症,促进患者症状缓解,且安全性良好。Objective To investigate the clinical therapeutic effect of ornidazole injection combined with latamoxef sodium on chronic pelvic inflammatory disease.Methods 96 patients with chronic pelvic inflammatory disease who were treated in our hospital from January 2022 to June 2023 were randomly divided into a control group(48 cases)and an observation group(48 cases).The control group was treated with latamoxef sodium,and the observation group was treated with ornidazole combined with latamoxef sodium.After 10 days,the therapeutic effects of the two groups were evaluated,and the differences between the two groups in pelvic effusion volume,clinical symptom scores,and serum inflammatory index levels before and after treatment were compared,and adverse reactions were observed.Results The total effective rate of the observation group was 93.75%,which was significantly higher than that of the control group(77.08%)(P<0.05).After treatment,compared with those before treatment,the pelvic effusion volume and symptom scores of the two groups were significantly decreased(P<0.05).Compared with the control group,the pelvic effusion volume and symptom scores of the observation group were lower(P<0.05).After treatment,the white blood cell count,C reactive protein and procalcitonin levels of the observation group were significantly lower than those of the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Ornidazole injection combined with latamoxef sodium has a good therapeutic effect on chronic pelvic inflammatory disease.It can more effectively reduce Ornidazole injection combined with latamoxef sodium has a good therapeutic effect on chronic pelvic inflammatory disease.It can more effectively reduce inflammation in the body,promote symptom relief in patients,and has good safety.

关 键 词：慢性盆腔炎 拉氧头孢钠 奥硝唑 疗效 炎症 

分 类 号：R969.2[医药卫生—药理学]