2020—2022年凤阳县农村上消化道癌发病现状及相关因素调查  

Incidence and related factors of upper gastrointestinal cancer in rural residents of Fengyang County,2020-2022

作　　者：代玉宏 李化龙 刘传芳 李大鹏[2] DAI Yuhong;LI Hualong;LIU Chuanfang;LI Dapeng(People´s Hospital of Fengyang County,Chuzhou,Anhui 233100,China;The First Affiliated Hospital of Bengbu Medical University)

机构地区：[1]安徽省凤阳县人民医院,安徽凤阳233100 [2]蚌埠医学院第一附属医院

出　　处：《华南预防医学》2024年第9期809-813,818,共6页South China Journal of Preventive Medicine

基　　金：安徽省教育厅自然科学重点项目(KJ2021A0798)。

摘　　要：目的了解调查凤阳县农村居民上消化道癌发病现状及其危险因素,为制定凤阳县上消化道癌防控策略提供参考依据。方法采用多阶段分层抽样方法,于2020年1月至2022年12月对安徽省凤阳县25个农村地区≥18岁常住农村人口进行上消化道癌初步检查、实验室检测及问卷调查,采用描述性分析方法对凤阳县农村居民上消化道癌发病情况进行分析,使用logistic回归模型对上消化道癌发病的危险因素进行分析。结果本研究共纳入4532名凤阳县常住农村居民并完成电子胃镜检查和可疑病灶的病理活检,发现上消化道癌81例,检出率为1.79%(81/4532)。多因素logistic回归分析显示,文化程度(高中以下OR=2.937,高中OR=2.206)、吸烟(OR=3.379)、过量饮酒(OR=2.165)、喜食腌制食品(OR=3.263)、饮茶(OR=0.519)、喜食油炸豆制品(OR=1.689)、萎缩性胃炎(OR=2.337)、幽门螺杆菌阳性(OR=1.910)均是凤阳县农村居民发生上消化道癌的影响因素(均P<0.05)。结论安徽省凤阳县农村居民上消化道癌发生率较高,需加强对存在不良饮食、饮酒习惯、合并萎缩性胃炎及幽门螺杆菌感染的高危人群进行早期筛查和定期体检,从而实现上消化道癌早诊断及早干预。Objective To investigate the incidence and risk factors of upper gastrointestinal cancer in rural residents of Fengyang County,and to provide a reference basis for the development of prevention and control strategies for upper gastrointestinal cancer in Fengyang County.Methods This study employed a multi-stage stratified sampling method,conducting preliminary examinations,laboratory tests,and questionnaires on the rural residents aged 18 and above in 25 rural communities of Fengyang County,Anhui Province,from January 2020 to December 2022.Descriptive analysis was used to analyze the incidence of upper gastrointestinal cancer in rural residents of Fengyang County,and Logistic regression models were used to analyze the risk factors of upper gastrointestinal cancer.Results A total of 4532 permanent rural residents in Fengyang County completed electronic gastroscopy and pathological biopsy of suspicious lesions,identifying 81 cases of upper gastrointestinal cancer,with a detection rate of 1.79%(81/4532).Multivariate logistic regression analysis indicated that education level(below high school OR=2.937,high school OR=2.206),smoking(OR=3.379),excessive drinking(OR=2.165),preference for pickled foods(OR=3.263),drinking tea(OR=0.519),preference for fried bean products(OR=1.689),atrophic gastritis(OR=2.337),and Helicobacter pylori positivity(OR=1.910)were influencing factors for upper gastrointestinal cancer in rural residents of Fengyang County.Conclusions The incidence of upper gastrointestinal cancer in rural residents of Fengyang County,Anhui Province,is relatively high.It is necessary to strengthen early screening and regular physical examinations for high-risk groups with poor dietary and drinking habits,combined with atrophic gastritis,and Helicobacter pylori infection,to achieve early diagnosis and intervention of upper gastrointestinal cancer.

关 键 词：上消化道癌 农村居民 流行特征 影响因素 

分 类 号：R195[医药卫生—卫生统计学]