芪参扶正片对化疗后白细胞减少症的临床防治效果研究  

Study on Clinical Prevention and Treatment Effect of Qishen Fuzheng Tablets on Leukopenia after Chemotherapy

作　　者：曾桂梅 肖勇辉 饶新辉 黄杰文 廖绮琳 吴莹莹 ZENG Guimei;XIAO Yonghui;RAO Xinhui;HUANG Jiewen;LIAO Qilin;WU Yingying(Meizhou Hospital of Traditional Chinese Medicine,Meizhou 514000,Guangdong,China)

机构地区：[1]梅州市中医医院,广东梅州514000

出　　处：《系统医学》2024年第20期172-175,共4页Systems Medicine

基　　金：广东省中医药管理局科研课题(20221396)。

摘　　要：目的探索芪参扶正片对化疗后白细胞减少症的防治效果。方法非随机选取2022年1月—2023年12月梅州市中医医院收治的60例化疗后白细胞减少症患者为研究对象,根据不同的治疗方式分为两组,各30例,治疗组给予芪参扶正片治疗,对照组给予西药治疗。比较两组患者治疗前后白细胞计数、中性粒细胞计数、中医证候积分。结果比较治疗后第5、10、15、21天白细胞计数,对照组白细胞计数降低幅度明显高于治疗组,差异有统计学意义(P均<0.05)。化疗第15天,对照组中性粒细胞计数明显低于治疗组,差异有统计学意义(P<0.05)。治疗组化疗后中医证候积分较化疗前降低,差异有统计学意义(P<0.05);对照组化疗前后比较,差异无统计学意义(P>0.05);化疗第21天,治疗组中医证候积分为(1.93±0.80)分,低于对照组的(4.33±1.58)分,差异有统计学意义(t=7.454,P<0.05)。结论芪参扶正片能够有效防治化疗后白细胞和中性粒细胞的减少,并能明显改善化疗患者的临床症状。Objective To explore the prevention and treatment effect of Qishen Fuzheng Tablets on leukopenia after chemotherapy.Methods From January 2022 to December 2023,sixty patients with leukopenia after chemotherapy ad⁃mitted to Meizhou Hospital of Traditional Chinese Medicine were non-randomly selected as the research objects.Ac⁃cording to different treatment methods,they were divided into two groups,thirty cases in each group.The treatment group was treated with Qishen Fuzheng Tablets,and the control group was treated with western medicine.The white blood cell count,neutrophil count and TCM syndrome score were compared between the two groups before and after treatment.Results Compared with the white blood cell count on the 5th,10th,15th and 21st day after treatment,the decrease of white blood cell count in the control group was significantly higher than that in the treatment group,and the differences were statistically significant(all P<0.05).On the 15 th day of chemotherapy,the neutrophil count in the control group was significantly lower than that in the treatment group,and the difference was statistically signifi⁃cant(P<0.05).The TCM syndrome score of the treatment group after chemotherapy was lower than that before chemo⁃therapy,and the difference was statistically significant(P<0.05).There was no significant difference in the control group before and after chemotherapy(P>0.05).On the 21st day of chemotherapy,the TCM syndrome score of treat⁃ment group was 1.93±0.80,which was lower than 4.33±1.58 in the control group,and the difference was statistically significant(t=7.454,P<0.05).Conclusion Qishen Fuzheng Tablets can effectively prevent and treat the decrease of white blood cells and neutrophils after chemotherapy,and can significantly improve the clinical symptoms of patients with chemotherapy.

关 键 词：芪参扶正片 化疗 白细胞减少症 防治效果 

分 类 号：R273[医药卫生—中西医结合]