超声引导下注射富血小板血浆治疗中度膝骨关节炎的临床疗效观察  

Clinical efficacy of ultrasound guided injection of platelet-rich plasma in the treatment of moderate knee osteoarthritis

作　　者：周炀 Zhou Yang(Hunan Provincial Rehabilitation Hospital,Changsha,Hunan 410007,China)

机构地区：[1]湖南省康复医院,湖南长沙410007

出　　处：《首都食品与医药》2024年第22期27-29,共3页Capital Food Medicine

摘　　要：目的 分析超声引导下注射富血小板血浆(PRP)治疗中度膝骨关节炎的临床疗效.方法 以我院2023年4月-2024年4月内收治的76例中度膝骨关节炎患者为本次研究对象,并以超声引导下注射药物差异分为SH组(38例,玻璃酸钠注射液)和PRP组(38例,富血小板血浆),对比分析两组药物应用差异.结果 PRP组患者的治疗总有效率显著高于SH组(P<0.05),治疗后1周及治疗结束时,PRP组患者NRS评分显著低于SH组(P<0.05),且治疗后的PRP组患者关节液中炎症因子水平及患肢血运指标参数RI均显著低于SH组(P<0.05),PSV、PI等患肢动脉血运参数及膝关节屈肌PT、膝关节伸肌PT、HSS评分均显著高于SH组(P<0.05).结论 超声引导下注射PRP治疗中度膝骨关节炎,可取得显著疗效,并且预后较佳,倡导在临床上应用.Objective To analyze the clinical efficacy of ultrasound guided injection of platelet-rich plasma(PRP)in the treatment of moderate knee osteoarthritis.Methods 76 patients with moderate knee osteoarthritis admitted to our hospital from April 2023 to April 2024 were selected as the subjects of this study,and were divided into SH group(38 cases,sodium hyaluronate injection)and PRP group(38 cases,platelet-rich plasma)according to the dfference of drug injection under ultrasound guidance.The difference of drug application between the two groups was compared and analyzed.Results The treatment effective rate of PRP group was significantly higher than that of SH group(P<0.05),and the NRS score of PRP group was significantly lower than that of SH group at 1 week after treatment and at treatment junction(P<0.05).After treatment,the levels of inflammatory factors in joint fluid and blood transport index parameters RI of affected limb in PRP group were significantly lower than those in SH group(P<0.05),and the arterial blood transport parameters of affected limb,such as PSV and PI,as well as knee flexor PT,knee extensor PT and HSS scores were significantly higher than those in SH group(P<0.05).Conclusion Ultrasound guided injection of PRP in the treatment of moderate knee osteoarthritis can achieve significant curative effect,and the prognosis is better,advocating clinical application.

关 键 词：中度膝骨关节炎 超声引导 富血小板血浆 

分 类 号：R684.3[医药卫生—骨科学]