小剂量红霉素及孟鲁司特钠治疗哮喘患儿分析  

Analysis of low dose erythromycin and montelukast sodium in the treatment of children with asthma

作　　者：杨洪 Yang Hong(Tanggu Maternity Hospital,Binhai New Area,Tianjin 300451,China)

机构地区：[1]天津市滨海新区塘沽妇产医院,天津300451

出　　处：《首都食品与医药》2024年第22期79-81,共3页Capital Food Medicine

摘　　要：目的 探讨小剂量红霉素及孟鲁司特钠治疗哮喘患儿的效果.方法 本研究以2020年1月-2023年1月时段就诊于我院儿科哮喘专病门诊的100例哮喘患儿为研究对象,随机进行对照组、观察组划分,每组各50例,对照组给予孟鲁司特钠治疗,观察组给予小剂量红霉素结合孟鲁司特钠治疗,比较两组临床疗效.结果 观察组治疗有效性高于对照组,差异明显(P<0.05);观察组治疗后FEV1、PEF、FEV1/FVC指标值均高于对照组,组间差异显著(P<0.05).结论 哮喘患儿接受小剂量红霉素结合孟鲁司特钠治疗,效果显著,应用价值更高.Objective To investigate the effect of low dose erythromycin and montelukast sodium on children with asthma.Methods In this study,100 children with asthma who were admitted to the pediatric asthma clinic of our hospital from January 2020 to January 2023 were selected as the research objects,and the control group and observation group were randomly divided into 50 cases each.The control group was given montelukast sodium treatment,and the observation group was given low dose erythromycin combined with montelukast sodium treatment,and the clinical efficacy of the two groups was compared.Results The treatment effectiveness of observation group was much higher than that of control group,the difference was significant(P<0.05).After treatment,FEV1,PEF and FEV1/FVC indexes in observation group were much higher than those in control group,and the differences were significant(P<0.05).Conclusion Small dose of erythromycin combined with montelukast sodium in the treatment of asthma children,the effect is significant,the application value is higher.

关 键 词：小剂量红霉素 孟鲁司特钠 哮喘 炎症因子 

分 类 号：R725.6[医药卫生—儿科]