中西医结合治疗抗结核药物所致胃肠道反应的临床观察  

Clinical observation on the combination of Traditional Chinese Medicine and Western medicine in the treatment of gastrointestinal reactions caused by anti tuberculosis drugs

作　　者：陆子玑 Lu Ziji(Zhongshan Second People's Hospital,Zhongshan,Guangdong 528400,China)

机构地区：[1]广东省中山市第二人民医院,广东中山528400

出　　处：《首都食品与医药》2024年第22期144-147,共4页Capital Food Medicine

摘　　要：目的 观察使用中医、中西医、西医治疗抗结核药物所致胃肠道不良反应的临床疗效.方法 选取2020年6月-2023年6月在中山市第二人民医院结核科住院并确诊肺结核且在使用四联抗结核药物后出现胃肠道反应的患者90例,采用随机数字表法均分为三组,分别使用中医、西医、中西医结合治疗,通过症状积分计算,并使用统计学分析对三组的治疗效果进行评价,同时对比组间疗效.结果 三组干预后的症状积分与干预前相比,差异有统计学意义(均P<0.01);疗效评估中医组显效24例,有效5例,无效1例,中西医组显效26例,有效3例,无效0例,西医组显效2例,有效9例,无效19例;从疗效例数观察,使用中药、中西药的显效、有效例数比西药组多.三组治疗前后症状分值差两两比较,中医组与中西医组差异不显著(P>0.05),中医组与西医组、中西医组与西医组两两比较,结果有显著差异(P<0.01).结论 中医、中西医结合治疗抗结核治疗出现的胃肠道反应效果良好,且两组效果与西医组对比有明显优势.Objective To observe the clinical efficacy of using Traditional Chinese Medicine,Traditional Chinese Medicine and Western medicine,and Western medicine to treat gastrointestinal adverse reactions caused by anti tuberculosis drugs.Methods Ninety patients who were hospitalized in the Tuberculosis Department of Zhongshan Second People's Hospital from June 2020 to June 2023 and were diagnosed with pulmonary tuberculosis and developed gastrointestinal reactions after using quadruple anti tuberculosis drugs were selected.They were randomly divided into three groups using a random number table method.Traditional Chinese Medicine,Western medicine,and a combination of Traditional Chinese Medicine and Western medicine were used for treatment,and symptom scores were calculated.Statistical analysis was used to evaluate the treatment effects of the three groups and to compare the therapeutic effects between groups.Results The symptom scores of the three groups after intervention were compared to before intervention,with statistical significance(all P<0.01);efficacy evaluation:there were 24 cases of significant effect,5 cases of effectiveness,and 1 case of ineffectiveness in the Traditional Chinese Medicine group,26 cases of significant effect,3 cases of effectiveness,and 0 cases of ineffectiveness in the Traditional Chinese Medicine group,and 2 cases of significant effect,9 cases of effectiveness,and 19 cases of ineffectiveness in the western medicine group;from the observation of the number of effective cases,the use of Traditional Chinese Medicine and Western medicine has more significant and effective cases than the Western medicine group.The difference in symptom scores before and after treatment among the three groups was compared pairwise,with P>0.05 between the Traditional Chinese Medicine group and the Traditional Chinese Medicine and Western medicine group.There was no statistically significant difference in the scores between the two groups,while the Traditional Chinese Medicine group and the Western medicine group,

关 键 词：中西医 结核 胃肠道反应 

分 类 号：R978.3[医药卫生—药品]