益气通络、活血化痰中药汤剂治疗冠心病心律失常的临床效果评价  

Clinical evaluation on the treatment of arrhythmia of coronary heart disease by supplementing Qi and clearing collaterals and promoting blood circulation and phlegm

作　　者：陈统 胡明振[1] 马金霞[1] CHEN Tong;HU Mingzhen;MA Jinxia(Department of Cardiovascular Medicine,Nanyang First People's Hospital,Nanyang,Henan 473000,China)

机构地区：[1]南阳市第一人民医院心血管内二科,河南南阳473000

出　　处：《现代医药卫生》2024年第22期3825-3828,3834,共5页Journal of Modern Medicine & Health

摘　　要：目的探讨在冠心病心律失常患者中应用益气通络、活血化痰中药汤剂的疗效。方法选取2019年10月至2020年12月该院收治的冠心病心律失常患者100例,采用随机数字表法分为研究组和对照组,每组50例。对照组采用美托洛尔缓释片治疗,研究组采用美托洛尔缓释片联合益气通络、活血化痰中药汤剂加减治疗。评价2组患者临床疗效、用药前后临床体征状况及用药安全性。结果研究组患者总有效率[96.00%(48/50)]明显高于对照组[82.00%(41/50)],治疗结束后缺血发作频率[(2.02±0.21)次/d]、脑钠肽水平[(86.35±35.14)μg/mL]、室性期前收缩频率[(461.38±81.21)次/d]、房性期前收缩频率[(473.82±93.14)次/d]均明显低于对照组[分别为(4.21±1.25)次/d、(156.08±38.24)μg/mL、(579.26±76.12)次/d、(559.68±99.42)次/d],缺血持续时间[(8.63±1.32)min/次]明显短于对照组[(14.52±2.06)min/次],差异均有统计学意义(P<0.05);研究组药物不良反应发生率[10.00%(5/50)]高于对照组[8.00%(4/50)],差异无统计学差异(P>0.05)。结论采用益气通络、活血化痰中药汤剂治疗冠心病心律失常患者效果确切,可提高临床疗效,改善临床体征,安全性佳。Objective To investigate the effect of supplementing Qi and clearing collaterals,promoting blood circulation and eliminating phlegm in patients with coronary heart disease and arrhythmia.Methods A total of 100 patients with arrhythmia in Nanyang First People's Hospital from October 2019 to December 2020 were selected.The patients were divided into the study group and the control group(50 cases/group)by randomly number table method.The control group was treated with metoprolol sustained-release tablets,while the study group was treated with metoprolol sustained-release tablets combined with Chinese herbal decoction for invigorating Qi and dredging collaterals,promoting blood circulation and resolving phlegm.The clinical efficacy,clinical signs and medication safety of the two groups were evaluated.Results The total effective rate of patients in the study group[96.00%(48/50)]was significantly higher than that in the control group[82.00%(41/50)].After treatment,the frequency of ischaemic episodes[(2.02±0.21)times/d],brain natriuretic peptide level[(86.35±35.14)μg/mL],ventricular preterm systole frequency[(461.38±81.21)times/d],and atrial preterm systole frequency[(473.82±93.14)times/d]were significantly lower than those of the control group at the end of the treatment[(4.21±1.25)times/d,(156.08±38.24)μg/mL,(579.26±76.12)times/d,and(559.68±99.42)times/d,respectively],and the duration of ischaemia[(8.63±1.32)min/d]was significantly shorter than that in the control group[(14.52±2.06)min/d],and the differences were statistically significant(P<0.05);the incidence of adverse drug reactions[10.00%(5/50)]compared with the control group[8.00%(4/50)],the difference was not statistically different(P>0.05).Conclusion The application of traditional Chinese medicine decoctions for tonifying Qi and unblocking collaterals,promoting blood circulation and resolving phlegm in the treatment of coronary heart disease and arrhythmia has a definite effect,can improve clinical efficacy,improve clinical signs,and have good safet

关 键 词：益气通络 活血化痰 中药汤剂 冠心病 心律失常 

分 类 号：R541.4[医药卫生—心血管疾病] R541.7[医药卫生—内科学]