自体毛囊干细胞移植生发技术的临床应用研究  

Clinical application of autologous hair follicle stem cell transplantation for hair growth

作　　者：陈玉文 陆志方 张胜方 梁靖雯 虞日安 覃宁 CHEN Yuwen;LU Zhifang;ZHANG Shengfang;LIANG Jingwen;YU Ri′an;QIN Ning(School of Health Medicine of Guangzhou Huashang University,Guangzhou,Guangdong,511300;Shengfang Clinic of Guangzhou Tianhe District,Guangzhou,Guangdong,510630;Medical College of Health of Guangzhou Huashang Vocational College,Guangzhou,Guangdong,511300)

机构地区：[1]广州华商学院健康医学院,广东广州511300 [2]广州天河区胜方诊所,广东广州510630 [3]广州华商职业学院健康医学院,广东广州511300

出　　处：《实用临床医药杂志》2024年第20期32-38,共7页Journal of Clinical Medicine in Practice

基　　金：国家自然科学基金面上项目(71773002)。

摘　　要：目的观察自体毛囊干细胞移植生发技术治疗脱发的临床疗效。方法选取2022年11月—2023年5月10例脱发患者,其中雄激素性5例,脂溢性5例。采用自体毛囊干细胞移植技术治疗,治疗前数据为对照组,治疗后数据为研究组,随访3~8个月。设计FPF评分法,采集数据,评价治疗效果。结果9例改善评分≥7分,1例改善评分为2分,治疗优良率为90%(9/10)。与对照组总评分(2.81±0.92)分相比,研究组总评分为(9.00±2.21)分,差异有统计学意义(P<0.001)。结论自体毛囊干细胞移植生发技术安全、疗效显著、适应证广。Objective To observe the clinical efficacy of autologous hair follicle stem cell transplantation for hair restoration in patients with alopecia.Methods Ten patients with alopecia,including five with androgenic alopecia and five with seborrheic alopecia,were selected from November 2022 to May 2023.They were treated with autologous hair follicle stem cell transplantation.Data before treatment were used as the control group,and data after treatment were used as the study group.Follow-up was conducted for 3 to 8 months.The FPF scoring system was designed to collect data and evaluate the treatment effect.Results Nine patients had an improvement score of≥7 points,and one patient had an improvement score of 2 points,with a treatment excellence rate of 90%(9/10).Compared with the total score of(2.81±0.92)points in the control group,the total score of the study group was(9.00±2.21)points,and the difference was statistically significant(P<0.001).Conclusion Autologous hair follicle stem cell transplantation for hair restoration is safe and effective,and has a broad range of indications.

关 键 词：脱发 自体毛囊干细胞 毛囊解剖学 生发技术 

分 类 号：R753.3[医药卫生—皮肤病学与性病学] R329.2[医药卫生—临床医学] R319