子午流注畲药化痰方经穴透入治疗痰热壅肺型社区获得性肺炎临床研究  

Clinical Study on Point Penetration with She Medicine Huatan Prescription at the Ebb and Flow of Midnight and Midday for Community-Acquired Pneumonia of Phlegm-Heat Obstructing the Lung Type

作　　者：叶璟 徐东娥[2] 蓝荣维 雷聪云 陈礼平[1] YE Jing;XU Dong'e;LAN Rongwei;LEI Congyun;CHEN Liping(Department of Cardiovascular Medicine,Lishui Hospital of Traditional Chinese Medicine,Lishui Zhejiang 323000,China;Department of Nursing,Tongde Hospital of Zhejiang Province,Hangzhou Zhejiang 310012,China)

机构地区：[1]丽水市中医院心血管内科,浙江丽水323000 [2]浙江省立同德医院护理部,浙江杭州310012

出　　处：《新中医》2024年第22期171-175,共5页New Chinese Medicine

基　　金：浙江省自然科学基金项目(LY20H280003);丽水市科技计划项目(2022GYX61);丽水市医学重点学科建设项目(3601017)。

摘　　要：目的:观察子午流注畲药化痰方经穴透入治疗痰热壅肺型社区获得性肺炎(CAP)的临床疗效。方法:78例痰热壅肺型CAP患者按随机数字表法分为对照组、试验组各39例。对照组采用常规西药对症处理,试验组在对照组基础上联用子午流注畲药化痰方经穴透入治疗。比较2组治疗前后中医证候积分、临床肺部感染评分(CPIS)、中性粒细胞计数(N)、C-反应蛋白(CRP)和降钙素原(PCT)水平;比较2组临床疗效及不良反应发生率。结果:研究过程中,试验组脱落1例,对照组脱落2例,最终试验组纳入研究38例,对照组纳入研究37例。治疗后,试验组总有效率为92.11%,高于对照组81.08%(P<0.05)。2组治疗后中医证候积分、CPIS评分及N、CRP、PCT水平均较治疗前降低(P<0.05),且试验组中医证候积分、CPIS评分及N、CRP、PCT水平均低于对照组(P<0.05)。2组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:子午流注畲药化痰方经穴透入治疗痰热壅肺型社区获得性肺炎疗效确切,能够减轻患者肺部感染,减轻炎症反应,安全性较高。Objective:To observe the clinical effect of point penetration with She medicine Huatan Prescription at the ebb and flow of midnight and midday for community-acquired pneumonia(CAP)of phlegm-heat obstructing the lung type.Methods:A total of 78 CAP patients of phlegm-heat obstructing the lung type were divided into the control group and the trial group,with 39 cases in each group,using a random number table method.The control group was treated with conventional western medicine for symptomatic treatment,and the trial group was treated with point penetration with She medicine Huatan Prescription at the ebb and flow of midnight and midday on the basis of the treatment of the control group.Compared the traditional Chinese medicine(TCM)syndrome scores,clinical pulmonary infection score(CPIS),neutrophil count(N),C-reactive protein(CRP),and procalcitonin(PCT)levels between the two groups before and after treatment.Compared the clinical efficacy and incidence of adverse reactions between the two groups.Results:During the research process,one case fell out of the trial group and two cases fell out of the control group.Finally,38 cases were included in the trial group and 37 cases were included in the control group.After treatment,the total effective rate was 92.11%in the trial group,which was higher than that of 81.08%in the control group(P<0.05).After treatment,the TCM syndrome scores,CPIS scores,and levels of N,CRP,and PCT in both groups were declined when compared with those before treatment(P<0.05),and the TCM syndrome score,CPIS score,and levels of N,CRP,and PCT in the trial group were lower than those in the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Point penetration with She medicine Huatan Prescription at the ebb and flow of midnight and midday is effective in treating CAP of phlegm-heat obstructing the lung type,which can reduce lung infection and inflammatory responses in patients,and has high safety.

关 键 词：社区获得性肺炎 痰热壅肺型 子午流注 畲药化痰方 经穴透入 炎症反应 

分 类 号：R563[医药卫生—呼吸系统]