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作 者:夏梦佳 姜宁[2] Type XIA Mengjia;JIANG Ning(Zhejiang Chinese Medical University,Hangzhou Zhejiang 310053,China;Department of Pediatrics,Hangzhou Red Cross Hospital,Hangzhou Zhejiang 311418,China)
机构地区:[1]浙江中医药大学,浙江杭州310053 [2]杭州市红十字会医院儿科,浙江杭州311418
出 处:《新中医》2024年第22期176-180,共5页New Chinese Medicine
基 金:浙江省中医药科技计划项目(2020ZB178)。
摘 要:目的:观察健脾贴敷联合调运枢纽推拿治疗脾胃虚弱型厌食症的临床疗效及对胃肠动力的影响。方法:选取103例脾胃虚弱型厌食症患儿作为研究对象,采用随机数字表法将患儿分为观察组51例与对照组52例。2组均给予葡萄糖酸锌口服溶液治疗,对照组加用健胃消食片治疗,观察组在对照组基础上给予健脾贴敷联合调运枢纽推拿治疗,2组均连续治疗2周。比较2组治疗前后中医证候评分、D-木糖排泄率、胃肠动力指标及血清锌、胃动素(MTL)、胃泌素(GAS)水平,并评估2组临床疗效及不良反应发生情况。结果:治疗后,观察组总有效率96.08%,高于对照组78.85%。治疗后,2组中医证候评分较治疗前降低(P<0.05),胃排空时间、胃半排空时间缩短(P<0.05),血清锌、MTL、GAS水平及D-木糖排泄率升高(P<0.05);观察组中医证候评分低于对照组,胃排空时间、胃半排空时间短于对照组(P<0.05),MTL、GAS及D-木糖排泄率高于对照组(P<0.05)。2组治疗后血清锌水平比较,差异无统计学意义(P>0.05)。2组治疗期间均未出现不良反应。结论:健脾贴敷联合调运枢纽推拿治疗脾胃虚弱型厌食症,能够调节患者胃肠激素及血清锌水平,改善胃排空功能,安全性较高。Objective:To observe the clinical effect of spleen-fortifying application combined with transport hub tuina on anorexia of spleen-stomach weakness type and its effect on gastrointestinal motility.Methods:A total of 103 anorexia children of spleen-stomach weakness type were selected as the research subjects,and were divided into the observation group(51 cases)and the control group(52 cases)using a random number table method.Both groups were treated with Oral Zinc Gluconate Solution,and the control group was treated with Jianwei Xiaoshi Tablets.The observation group was treated with spleen-fortifying application combined with transport hub tuina on the basis of the treatment of the control group.Both groups were treated continuously for two weeks.Compared the traditional Chinese medicine(TCM)syndrome scores,D-xylose excretion rates,gastrointestinal motility indexs and the levels of zinc,motilin(MTL),and gastrin(GAS)in serum before and after treatment in the two groups,and evaluated the clinical effects and incidence of adverse reactions in the two groups.Results:After treatment,the total effective rate was 96.08%in the observation group,which was higher than that of 78.85%in the control group.The TCM syndrome scores in the two groups were decreased when compared with those before treatment(P<0.05),the gastric emptying time and gastric semi-emptying time were shortened(P<0.05),and the levels of zinc,MTL,GAS,and D-xylose excretion rates in serum were increased(P<0.05).The TCM syndrome scores in the observation group were decreased,the gastric emptying time and gastric semi-emptying time were shortened(P<0.05),and levels of MTL,GAS,and D-xylose excretion rates were increased when compared with the control group(P<0.05).There was no significant difference in serum zinc levels between the two groups after treatment(P>0.05).No adverse reactions occurred during the treatment period in both groups.Conclusion:Spleen-fortifying application combined with transport hub tuina can treat anorexia of spleen-stomach weakness type,r
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