基于中医皮部和通道理论的中药经皮给药的传输体系构建  

Construction on a transmission system for transdermal delivery of Chinese medicine based on the theory of cutaneous region and channel in traditinal Chinese medicine

作　　者：薛凯阳 万开龙 宋信莉 卢筱潇 卢春霞 张宁 崔瑾 XUE Kaiyang;WAN Kailong;SONG Xinli;LU Xiaoxiao;LU Chunxia;ZHANG Ning;CUI Jin(Guizhou University of Traditional Chinese Medicine,Guiyang 550025,China;The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang 550002,China)

机构地区：[1]贵州中医药大学,贵阳550025 [2]贵州中医药大学第一附属医院,贵阳550002

出　　处：《中华中医药杂志》2024年第11期6171-6174,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：贵州省科技计划项目(No.黔科合支撑〔2023〕一般240)。

摘　　要：中药经皮给药历久弥新、方法众多,是中医药外治体系的重要组成部分。文章依托中医“皮部”及“通道”理论,尝试从皮部及其附属结构出发,以皮部-络脉网状通道、气门-玄府微观通道、皮腠-三焦膜性通道等不同维度论述中医皮部和通道的分类分布、形态结构、生理功能,及其与现代实质结构和信息分子的强相关性,解析中药经皮给药的生物传输路径,以期为进一步揭示外治法中药经皮给药的生物传输机制奠定中医理论基础。Transdermal administration of Chinese medicine is an important component of the external treatment system of traditional Chinese medicine(TCM),with its timeless and numerous methods.Based on the theory of‘cutaneous region’and‘channel’,this article attempts to start from the skin and its affiliated structures,and discuss the classification and distribution,morphological structure,physiological function,and strong correlation with modern substantive structure and information molecules of TCM cutaneous region and channels from different dimensions such as the skin collateral network channel,the spiracle Xuanfu micro channel,and the skin striae Sanjiao membrane channel,to lay a theoretical foundation for further revealing the biological transport mechanism of TCM transdermal administration.

关 键 词：经皮给药 皮部 通道理论 经隧 传输途径 

分 类 号：R28[医药卫生—中药学]