二氧化碳点阵激光联合羟氯喹治疗对玫瑰痤疮患者面部红斑情况及生活质量的影响  

Impact of Carbon Dioxide Fractional Laser Combined with Hydroxychloroquine on Facial Erythema and Quality of Life in Patients with Rosacea

作　　者：程露 徐继鹏[1] CHENG Lu;XU Jipeng(Department of Dermatology,the Affiliated Hospital of Xinyang Institute of Vocational Technology,Xinyang 464000,China)

机构地区：[1]信阳职业技术学院附属医院皮肤科,河南信阳464000

出　　处：《临床医学工程》2024年第11期1305-1306,共2页Clinical Medicine & Engineering

摘　　要：目的探讨二氧化碳(CO_(2))点阵激光联合羟氯喹治疗对玫瑰痤疮患者面部红斑情况及生活质量的影响。方法选取2019年3月至2022年12月我院收治的80例玫瑰痤疮患者,随机分为单一组(40例)和联合组(40例)。单一组给予羟氯喹治疗,联合组给予CO_(2)点阵激光联合羟氯喹治疗,两组均连续治疗3个月。比较两组的面部红斑情况、生活质量及不良反应发生情况。结果联合组治疗1个月、2个月、3个月后的CEA评分、DLQI评分均低于单一组(P<0.05)。联合组治疗期间不良反应发生率为7.50%,与单一组的2.50%比较差异无统计学意义(P>0.05)。结论CO_(2)点阵激光联合羟氯喹治疗可明显改善玫瑰痤疮患者的面部红斑情况,提升其生活质量,且安全可靠。Objective To analyze the effect of carbon dioxide(CO_(2))fractional laser combined with hydroxychloroquine on facial erythema and quality of life in patients with rosacea.Methods 80 patients with rosacea admitted to our hospital from March 2019 to December 2022 were selected and randomly divided into single group(40 cases)and combined group(40 cases).The single group was treated with hydroxychloroquine,and the combined group was treated with CO_(2) fractional laser combined with hydroxychloroquine.Both groups received continuous treatment for 3 months.The facial erythema,quality of life and adverse reactions were compared between the two groups.Results After 1 month,2 months and 3 months of treatment,the CEA score and DLQI score of the combined group were lower than those of the single group(P<0.05).The incidence of adverse reactions during treatment in the combined group was 7.50%,which had no statitsical difference with 2.50%in the single group(P>0.05).Conclusions CO_(2) fractional laser combined with hydroxychloroquine can significantly improve the facial erythema in patients with rosacea,and improve the quality of life,which is safe and reliable.

关 键 词：玫瑰痤疮 CO_(2)点阵激光 羟氯喹 面部红斑 生活质量 不良反应 

分 类 号：R758.73[医药卫生—皮肤病学与性病学]