Nascent mRNA damage:depot and disposal  

作　　者：Mark Helm Marie-Luise Winz 

机构地区：[1]Institute of Pharmaceutical and Biomedical Science(IPBS),Johannes Gutenberg University Mainz,Staudingerweg 5,55128 Mainz,Germany

出　　处：《Signal Transduction and Targeted Therapy》2024年第9期3546-3547,共2页信号转导与靶向治疗（英文）

基　　金：funded by Deutsche Forschungsgemeinschaft(DFG,German Research Foundation)[project number 439669440 TRR319 RMaP TP C01/C03 to M.H.TP B05 to M.-L.W.].

摘　　要：In a recent study published in Cell,Zhou et al.1 have characterized a highly unusual behavior of specialized stress granules(SG),driven by metabolism of UV-damaged pre-mRNA.These cytoplasmic SGs are characterized by an unusual content of intronic sequences and the double-stranded RNA(dsRNA)specific helicase DHX9,both of which are usually found in the nucleus.

关 键 词：METABOLISM DAMAGE 

分 类 号：Q24[生物学—细胞生物学]