动物病原感染性呼吸系统疾病兽药研究进展及新药研发趋势分析  

Research Progress of Veterinary Drugs for Animal Pathogenic Infectious RespiratoryDiseases and Analysis of New Drug Research and Development

作　　者：蔡子雯 孙志刚[2] 司晓慧 吕若一 刘晓晔[1,2] CAI Ziwen;SUN Zhigang;SI Xiaohui;L Ruoyi;LIU Xiaoye(Beijing Key Laboratory of Traditional Chinese Veterinary Medicine,Beijing University of Agriculture,Beijing 102206,China;Animal Science and Technology College,Beijing University of Agriculture,Beijing 102206,China)

机构地区：[1]北京农学院,兽医学(中医药)北京市重点实验室,北京102206 [2]北京农学院动物科学技术学院,北京102206

出　　处：《畜牧兽医学报》2024年第11期4872-4889,共18页ACTA VETERINARIA ET ZOOTECHNICA SINICA

基　　金：国家自然科学基金(32202864);北京市教育委员会科学研究计划(KM202310020006);北京市科学技术协会青年人才托举工程(BYESS2023192);北京农学院青年教师科研创新能力提升计划(QJKC2022028);北京农学院科技创新“火花行动”支持计划(BUA-HHXD2022007,BUA-HHXD2023002);市属高校分类发展——都市农林特色教师队伍建设(11000024T000002961733)。

摘　　要：动物病原感染性呼吸系统疾病对畜禽养殖业和宠物医疗构成重大挑战,病原体导致的传染性疾病不仅危害动物健康,也影响人类公共卫生安全。目前,针对这些疾病的新兽药开发面临瓶颈。本文重点归纳总结我国动物病原感染性呼吸疾病兽药的研究进展,针对我国动物病原感染性呼吸系统疾病疾病兽药种类、研发时间、用药规律,以及兽药剂型等特点进行了全面总结,以期归纳我国动物病原感染性呼吸道疾病兽药研发进展。同时本文针对动物呼吸系统兽药中化药和中药类别、剂型、临床应用等特点,分析出我国新兽药的未来研发趋势需要侧重于现有药物的高效应用,重点研究药物剂型优化和多靶点药物的开发,本文旨在为有效防控动物病原感染性呼吸系统疾病提供用药方案,为兽医临床新兽药未来研发的方向提供参考。Infectious respiratory diseases caused by animal pathogens pose a major challenge to livestock and poultry breeding and pet medical care.Infectious diseases caused by pathogens not only endanger animal health,but also affect human public health safety.At present,the development of new veterinary drugs for these diseases is facing bottlenecks.This paper focuses on summarizing the research progress of veterinary drugs for animal pathogenic infectious respiratory diseases in China,and comprehensively summarizes the characteristics of veterinary drugs for animal pathogenic infectious respiratory diseases in China,such as types,research and development time,medication rules,and veterinary drug dosage forms,in order to summarize the research and development progress of veterinary drugs for animal pathogenic infectious respiratory diseases in China.At the same time,according to the characteristics of the categories,dosage forms and clinical applications of chemical drugs and traditional Chinese medicine in animal respiratory veterinary drugs,this paper analyzes that the future research and development trend of new veterinary drugs in China needs to focus on the efficient application of existing drugs,focusing on the optimization of drug dosage forms and the development of multi-target drugs.The purpose of this paper is to provide a medication plan for the effective prevention and control of animal pathogenic infectious respiratory diseases,and to provide a reference for the future research and development direction of veterinary clinical new veterinary drugs.

关 键 词：兽药 动物呼吸系统疾病 研究进展 新药研发趋势 

分 类 号：S859.792[农业科学—临床兽医学]