新生儿泪囊炎发病危险因素分析  

Analysis of risk factors of neonatal dacryocystitis

作　　者：周文轲 何俐莹[1] 陶雪莹 岑超 黎琦 Zhou Wenke;He Liying;Tao Xueying;Cen Chao;Li Qi(Department of Ophthalmology,Otorhinolaryngology,Chongqing Health Center for Women and Children,Women and Children’s Hospital of Chongqing Medical University,Chongqing 400000,China)

机构地区：[1]重庆市妇幼保健院重庆医科大学附属妇女儿童医院眼耳鼻喉科,重庆400000

出　　处：《发育医学电子杂志》2024年第6期451-456,共6页Journal of Developmental Medicine (Electronic Version)

基　　金：重庆市社会事业与民生保障科技创新专项重点研发资助项目(cstc2017shms-zdyfX0049)。

摘　　要：目的探讨新生儿泪囊炎发病的影响因素,研究泪道冲洗的最优时机,以便为新生儿泪囊炎的预防和治疗提供可靠的临床依据。方法采用回顾性病例对照研究方法,收集2019年3月至2022年8月在重庆市妇幼保健院诊治的新生儿泪囊炎患儿553例以及正常对照组553例,对照组为非调查因素相同的非新生儿泪囊炎。在病历系统中提取孕母病史、分娩方式以及新生儿胎龄、出生体质量等相关信息,对比不同月龄新生儿首次行泪道冲洗后泪囊炎的治愈率。统计学方法采用单因素和多因素Logistic回归分析以及χ^(2)检验。结果多因素Logistic回归分析结果表明,剖宫产、男婴、母亲妊娠期合并全身疾病是新生儿泪囊炎发病的危险因素(P值均<0.05)。剖宫产新生儿罹患泪囊炎的概率是顺产的1.279倍,妊娠期合并全身疾病孕妇娩出新生儿罹患泪囊炎的概率是妊娠期健康孕妇的1.399倍。而出生胎龄、出生体质量、孕妇民族等与新生儿泪囊炎均无统计学差异(P值均>0.05)。首次行泪道冲洗月龄不同,新生儿泪囊炎的治愈率差异有统计学意义(P=0.038),且行泪道冲洗治愈率最高的泪囊炎患儿首次冲洗月龄为2~3月龄(治愈率为28.25%)。结论剖宫产、男婴、母亲妊娠期合并全身疾病可能会导致新生儿泪囊炎的发生,加强孕期保健宣教,在各方面条件合适的情况下鼓励孕妇自然分娩,可有效减少新生儿泪囊炎的发生。对于新生儿泪囊炎患儿,建议首次冲洗月龄为2~3月龄。Objective To investigate the influencing factors of neonatal dacryocystitis and explore the best time for irrigation of lacrimal passage,so as to provide a reliable clinical basis for the prevention and treatment of neonatal dacryocystitis.Method A retrospective case-control study was used to collect 553 cases of neonatal dacryocystitis treated in Chongqing Health Center for Women and Children from March 2019 to August 2022 and 553 cases of normal control group.The control group was non-neonatal dacryocystitis with the same non-investigation factors.Relevant information such as maternal medical history,delivery mode,gestational age and fetal weight of infants were extracted from the medical record system,the cure rate of neonatal dacryocystitis after first irrigation of lacrimal passage at different months was compared.The statistical methods performed by univariate analysis and multivariate Logistic regression analysis,χ^(2) test.Result The results of multivariate Logistic regression analysis showed that cesarean section,male,maternal pregnancy combined with systemic disease were the risk factors for neonatal dacryocystitis(all P<0.05),the probability of neonatal dacryocystitis during cesarean section was 1.279 times that of vaginal delivery,and the probability of dacryocystitis in newborns of pregnant women with systemic diseases during pregnancy was 1.399 times that of healthy pregnant women during pregnancy.Gestational age,birth weight of infants and maternal ethnicity were not significantly different from neonatal dacryocystitis(all P>0.05).The cure rate of neonatal dacryocystitis was statistically significant with different months of first irrigation of lacrimal passage(P=0.038),and the highest cure rate of the first irrigation of lacrimal passage was 2 to 3 months(the cure rate was 28.25%).Conclusion Cesarean section,male and maternal pregnancy combined with systemic diseases may lead to neonatal dacryocystitis.Strengthening the health education during pregnancy and encourage pregnant women to give birth

关 键 词：新生儿泪囊炎 发病危险因素 泪道冲洗 回归分析 

分 类 号：R722.1[医药卫生—儿科]