口腔颌面部创伤患者术后感染的影响因素分析及风险预测模型的构建  

Analysis of influencing factors of postoperative infection in patients with oral and maxillofacial trauma and construction of risk prediction model

作　　者：张俊 李媛媛[1] 邓四海 詹骏 ZHANG Jun;LI Yuanyuan;DENG Sihai;ZHAN Jun(Department of Stomatology,Pingxiang People's Hospital,Pingxiang,Jiangxi,337000,China;Department of Laboratory,Pingxiang Maternal and Child care,Pingxiang,Jiangxi,337000,China)

机构地区：[1]萍乡市人民医院口腔科,江西萍乡337000 [2]萍乡市妇幼保健院检验科,江西萍乡337000

出　　处：《当代医学》2024年第19期21-24,共4页Contemporary Medicine

基　　金：江西省卫生健康委科技计划项目(202311717)。

摘　　要：目的分析口腔颌面部创伤患者术后感染的影响因素,并构建Nomogram预测模型。方法回顾性分析2021年5月至2022年10月萍乡市人民医院收治的160例口腔颌面部创伤患者的临床资料。统计患者感染情况,分析影响口腔颌面部创伤患者术后感染的影响因素,并采用内部数据验证Nomogram模型的临床效能。结果160例口腔颌面部创伤患者中,感染55例。感染与未感染患者性别、体重指数(body mass index,BMI)比较差异无统计学意义;感染患者年龄大于未感染患者,糖尿病、伤口有异物、手术类型为Ⅲ类、未使用抗菌药物占比均高于未感染患者,手术时间长于未感染患者,差异有统计学意义(P<0.05)。年龄(>54岁)、糖尿病(是)、手术时间(>3 h)、伤口异物(有)、手术切口类型(Ⅲ类)、抗菌药物使用(无)是影响口腔颌面部创伤患者术后感染的危险因素(P<0.0.5)。模型预测的风险C-index为0.733(95%CI:0.681~0.838);预测口腔颌面部创伤患者术后感染的风险阈值>0.07。结论年龄(>54岁)、糖尿病(是)、手术时间(>3 h)、伤口异物(有)、手术切口类型(Ⅲ类)、抗菌药物使用(无)是影响口腔颌面部创伤患者术后感染的危险因素,且基于变量构建的模型有较好的预测能力。Objective To analyze the influencing factors of postoperative infection in patients with oral and maxillofacial trauma and establish a Nomogram prediction model.Methods The clinical data of 160 patients with oral and maxillofacial trauma admitted to Pingxiang People's Hospital from May 2021 to October 2022 were retrospectively analyzed.The infection of patients was counted,the influencing factors of postoperative infection in patients with oral and maxillofacial trauma were analyzed,and the clinical efficacy of Nomogram model was verified by internal data.Results Among 160 patients with oral and maxillofacial trauma,55 cases were infected.There were no significant differences in gender and body mass index(BMI)between infected and uninfected patients;the age of the infected patients was older than that of the non-infected patients,the proportion of diabetes,foreign bodies in the wound,typeⅢof surgery incision,and unused antibiotics was higher than that of the non-infected patients,and the operation time was longer than that of the non-infected patients,the differences were statistically significant(P<0.05).Age(>54 years old),diabetes(yes),operation time(>3 h),foreign body in wound(there),type of surgical incision(Ⅲ),use of antibiotics(none)were the risk factors for postoperative infection in patients with oral and maxillofacial trauma(P<0.05);the risk C-index predicted by the model was 0.733(95%CI:0.681-0.838).The risk threshold of postoperative infection in patients with oral and maxillofacial trauma was predicted to be>0.07.Conclusion Age(>54 years old),diabetes(yes),operation time(>3 h),foreign body in wound(there),type of surgery incision(Ⅲ),use of antibiotics(none)are the risk factors of postoperative infection in patients with oral and maxillofacial trauma,and the model based on variables has good predictive power.

关 键 词：口腔颌面部创伤 感染 影响因素 Nomogram预测模型 

分 类 号：R473.6[医药卫生—护理学]