94例妇科门诊就诊人群阴道微生态分布特征情况及临床症状调查分析  

Investigation and analysis of vaginal microecological distribution characteristics and clinical symptoms in 94 gynecological outpatients

作　　者：张彦[1] 魏武 葛丽丽 ZHANG Yan;WEI Wu;GE Lili(Department of Obstetrics and Gynecology,Fengcheng Traditional Chinese Medicine Hospital,Yichun,Jiangxi,331100,China)

机构地区：[1]丰城市中医院妇产科,江西宜春331100

出　　处：《当代医学》2024年第19期128-132,共5页Contemporary Medicine

摘　　要：目的分析94例妇科门诊就诊人群阴道微生态分布特征及临床症状情况。方法选取2021年1—12月丰城市中医院妇科门诊就诊的94例女性作为研究对象,采集其阴道分泌物,进行微生态检查,根据阴道微生态情况分为正常组、微生态失调组与炎症组。比较3组临床特征、阴道微生态系统功能学指标[阴道微环境pH值、过氧化氢(hydrogen peroxide,H2O2)、白细胞酯酶(leukocyte esterase,LE)、唾液酸苷酶(sialy glycoside enzyme,SNa)、N-乙酰葡萄糖胺(acetylglucosaminidase,GlcNac)、β-葡萄糖醛酸苷酶(β-glucuronidase,GUS)]症状体征评分及白带情况,分析阴道微生态系统形态学检测指标。结果94例患者中,正常组32例(34.04%),微生态失调组39例(41.49%),炎症组23例(24.47%);3组年龄、体质量、体重指数、婚姻状况、孕次、产次、文化程度、人乳头瘤病毒感染、家庭月收入及月经情况比较差异无统计学意义;乳酸杆菌+级占比43.62%,菌群密集度Ⅳ级占比53.19%,菌群多样性Ⅳ级占比48.94%,Nugent评分≤3分占比39.36%,菌丝孢子检出情况占比12.77%和滴虫检出情况占比5.32%;3组pH及H2O2、LE、SNa、GlcNac、GUS阳性率比较差异有统计学意义(P<0.05);炎症组pH值、SNa、GUS阳性率均高于正常组与微生态失调组,LE、GlcNac阳性率均高于正常组,微生态失调组pH值、LE、GlcNac阳性率均高于正常组,H2O2阳性率低于正常组,差异有统计学意义(P<0.05);炎症组症状体征评分高于微生态失调组,炎症组症状体征评分、白带增多发生率均高于正常组,差异有统计学意义(P<0.05),正常组与微生态失调组白带增多发生率比较差异无统计学意义。结论妇阴道微生态检测可整体全面评估阴道微生态情况,同时诊断多种阴道炎症及混合性阴道感染,指导临床对症治疗,促进阴道免疫调节和阴道微生态平衡,降低阴道感染复发率。Objective To analyze the vaginal microecological distribution characteristics and clinical symptoms in 94 gynecological outpatient visits.Methods 94 women attending the gynecology outpatient clinic of Fengcheng City Hospital of Traditional Chinese Medicine from January to December 2021 were selected as study subjects,they were divided into the normal group,microecological imbalance group and the inflammation group according to vaginal microecology.Their vaginal secretions were collected for microecological examination,the clinical characteristics,vaginal microecosystem functional indicators(vaginal microenvironment pH,hydrogen peroxide[H2O2],leukocyte esterase[LE],sialy glycoside enzyme[SNa],N-acetylglucosaminidase[GlcNac],andβ-glucuronidase[GUS])symptom and sign scores and leucorrhea were compared among the three groups,the morphological indicators for the detection of microecosystem were analyzed.Results Among the 94 patients,there were 32 cases(34.04%)in the normal group,39 cases(41.49%)in the microecological imbalance group,and 23 cases(24.47%)in the inflammation group;there were no significant differences in age,body mass,body mass index,marital status,gravidity,parity,education level,human papillomavirus infection,family monthly income and menstruation among the three groups;Lactobacillus+accounted for 43.62%,flora densityⅣaccounted for 53.19%,flora diversityⅣaccounted for 48.94%,Nugent score≤3 scores accounted for 39.36%,mycelium spore detection accounted for 12.77%and trichomonad detection accounted for 5.32%;there were significant differences in pH and the positive rates of H2O2,LE,SNa,GlcNac and GUS among the three groups(P<0.05);the positive rates of pH,SNa and GUS in the inflammation group were higher than those in the normal group and the microecological imbalance group,the positive rates of LE and GlcNac in the inflammation group were higher than those in the normal groupl,the positive rates of pH,LE and GlcNac in the microecological imbalance group were higher than those in the normal group,

关 键 词：阴道微生态 形态学 功能学 微生态失调 

分 类 号：R71[医药卫生—妇产科学]